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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Different types of skin cells play specific roles in development, healing, and cancer.

Noggin is necessary to start the hair growth phase in skin after birth.

Androgens can both increase and decrease hair growth in different parts of the body.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

PGD2 stops hair growth and is higher in bald men with AGA.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Lactate production is important for activating hair growth stem cells.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Sebocytes play a key role in controlling androgen levels in human skin.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Fungi-produced compounds can change plant root growth.

Dermatologists need to understand hair products to treat hair and scalp issues better.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Researchers found 19 genes important for root hair growth in a plant called Arabidopsis.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.