November 2022 in “Journal of the Endocrine Society” A 21-year-old male with a rare genetic disorder experienced sudden hair loss and high DHEAS levels, likely due to a condition similar to PCOS, usually seen in women.
April 2019 in “Journal of the Endocrine Society” A young patient with unusual insulin resistance and high testosterone levels had a rare INSR gene mutation.
24 citations,
April 2008 in “Fertility and sterility” Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.
The case shows the difficulty in diagnosing certain conditions when standard tests are negative.
16 citations,
August 1967 in “JAMA” Oral contraceptives may cause hair loss in women.
November 2022 in “Journal of the Endocrine Society” A boy with a new NR5A1 gene mutation has a sex development disorder without affecting his adrenal glands.
August 2022 in “IntechOpen eBooks” Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.
January 2014 in “European Geriatric Medicine” A postmenopausal woman's virilization was caused by a rare ovarian tumor that was hard to detect but was successfully treated with surgery.
21 citations,
May 2005 in “Journal of the American Veterinary Medical Association” The exact cause of growth hormone-responsive alopecia in dogs is unclear.
A new mutation in the CYP11B1 gene was found in a woman with mild hyperandrogenemia, a rare cause of non-classic congenital adrenal hyperplasia.
11 citations,
October 2003 in “Postgraduate Medical Journal” Doctors often diagnose Cushing's syndrome late, which worsens symptoms; earlier detection is needed.
29 citations,
February 2011 in “PloS one” Astressin-B can reverse and prevent hair loss in stressed mice.
52 citations,
October 2004 in “Veterinary dermatology” Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.
April 2020 in “Journal of the Endocrine Society” Taking thyroid medication reduced the patient's pituitary gland swelling and improved her symptoms.
October 2023 in “Journal of the Endocrine Society” A woman was diagnosed with Sheehan's syndrome and a rare complication of diabetes insipidus 33 years after symptoms began, improving with hormone therapy.
January 2017 in “IMC Journal of Medical Science” A rare endocrine disorder, APS 1, was diagnosed in a 26-year-old man in Bangladesh.
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9 citations,
June 2014 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Blood AMH levels are higher in women with PCOS than in those with other similar conditions.
42 citations,
October 2004 in “Experimental and Clinical Endocrinology & Diabetes” The main cause of excessive hair growth in Turkish women is Polycystic ovary syndrome, but in about one fifth of cases, the reason for high male hormone levels is unknown.
34 citations,
March 2003 in “Veterinary Dermatology” Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.
October 2023 in “Journal of the Endocrine Society” Losing weight and taking birth control pills can greatly improve severe male hormone excess in women with PCOS.
82 citations,
January 2000 in “Hormone Research in Paediatrics” DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.
January 2013 in “Revista Clínica Española” A postmenopausal woman's increased male hormone levels were successfully treated with surgery.
December 2023 in “JCEM case reports” A new gene variant causes glucocorticoid resistance in a mother and son.
11 citations,
January 2013 in “Indian Journal of Endocrinology and Metabolism” A woman with a rare adrenal tumor and hormonal disorder had improved testosterone levels after surgery, but her menstrual irregularities continued.
16 citations,
January 2008 in “Acta dermato-venereologica” Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.
22 citations,
January 2011 in “Indian Journal of Dermatology/Indian journal of dermatology” Cow placenta extract may help hair grow by increasing a growth factor but is less effective than minoxidil.
A young woman with kidney failure had hair loss due to a common hormonal disorder, which improved with hormone therapy.
December 2017 in “Journal of pediatric surgery case reports” A toddler with a rare adrenal gland tumor causing male-like physical changes was successfully treated with surgery.
October 2024 in “Journal of the Endocrine Society” Acute illnesses like sepsis can disrupt thyroid hormone balance without central hypothyroidism.