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The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Oestrogens are key for bone growth during puberty in both boys and girls.

Women with PCOS have lower quality of life, especially in mental health and energy, and managing weight can help improve it.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.