13 citations
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March 2015 in “Steroids” The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.
5 citations
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December 2021 in “Pediatric investigation” Testosterone undecanoate safely and effectively increased penis size in male children with 5-alpha-reductase deficiency.
Eriocitrin and silymarin might be effective for hair loss treatment and need more research.
Marine sponges from Tabuhan Island can inhibit enzymes linked to Alzheimer's and hair loss.
42 citations
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August 2007 in “Endocrinology and metabolism/American journal of physiology: endocrinology and metabolism” Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.
37 citations
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August 2019 in “Journal of The American Academy of Dermatology” Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.
December 2023 in “International Journal of Molecular Sciences” Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.
32 citations
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May 2010 in “Pharmacopsychiatry” Finasteride reduces new brain cells in male mice, possibly causing depression.
153 citations
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November 2004 in “Current Medicinal Chemistry” The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
24 citations
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January 2014 in “The American Journal of Chinese Medicine” The leaves of Platycladus orientalis have potential health benefits but require more research for safety and understanding how they work.
11 citations
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September 2020 in “OncoTargets and Therapy” Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.
10 citations
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August 2019 in “International Journal of Cosmetic Science” Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.
10 citations
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December 2005 in “Aktuelle Dermatologie” Alfatradiol (0.025%) is an effective and safe treatment for hair loss in both women and men.
8 citations
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January 1989 in “Annual Reports in Medicinal Chemistry” Hair loss from alopecia areata and androgenetic alopecia can be treated, but more effective and safer treatments are needed.
7 citations
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September 2021 in “Journal of the European Academy of Dermatology and Venereology” Early treatment of fibrosing alopecia in a pattern distribution may improve outcomes.
7 citations
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January 1994 in “Annual Reports in Medicinal Chemistry” Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
6 citations
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January 2008 in “Medical Hypotheses” Male pattern baldness might have evolved to help protect against prostate cancer by increasing UV radiation on the scalp.
2 citations
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March 2012 in “Nature Reviews Endocrinology” The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.
1 citations
,
July 2013 in “JAMA Dermatology” Dermatologists should address erectile dysfunction in patients with skin conditions to improve their quality of life.
1 citations
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November 1996 in “Journal of Cutaneous Medicine and Surgery” Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.
Eclipta alba L. (Urang-Aring) can help treat hair loss.
December 2020 in “Current Sexual Health Reports” Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
January 2017 in “Korean Journal of Pharmacognosy” Modified red ginseng extract promotes hair growth and has antioxidant and anti-inflammatory effects.
January 2003 in “Elsevier eBooks” Androgens and other hormones affect hair growth and skin conditions like acne.
July 1993 in “Inpharma Weekly” Dicentrine reduced heart disease risk factors in rats, T-588 protected mice brains without side effects, Provir blocked herpes virus and lessened mouse symptoms, and LY191704 could treat hair loss and prostate issues.
June 2017 in “Journal of The European Academy of Dermatology and Venereology” Alopecia patients have higher heart disease risk; statins and finasteride may help.
September 1997 in “Journal of The European Academy of Dermatology and Venereology” New treatment improves male hair loss.
112 citations
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October 2005 in “Mayo Clinic Proceedings” Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.
98 citations
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May 2013 in “Journal of The American Academy of Dermatology” Dutasteride may help stabilize Frontal Fibrosing Alopecia, but more research is needed.
98 citations
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August 2004 in “BJU international” Medications have become the main treatment for enlarged prostate symptoms, replacing surgery and watchful waiting.