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Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Testosterone and some of its forms can strongly stimulate oil gland growth in skin.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Topical spironolactone cream doesn't cause hormone-related side effects in the body.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Researchers made two new compounds that could be used for medicine.

Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Hair loss causes differ between men and women due to changes in hormone levels and inflammation-related pathways.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

The study created a new method to test drugs that affect hormone processing in skin.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.

Male hormones control a specific gene in hamster skin, with different hormones having varying effects.