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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

DHT affects testicular development and regulates spermatogenesis in some fish.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

Testosterone's muscle-building effects do not require its conversion to DHT.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

New tests detect finasteride and dutasteride in urine quickly and easily.

Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.

Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

Pueraria mirifica extract may help treat benign prostatic hyperplasia.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Finasteride affects prostate weights and pituitary activity differently with age.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Finasteride helps protect brain in old male rats.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

Certain Dibenzo derivatives may help treat prostate cancer.

New drug dutasteride effectively treats hair loss, but use cautiously due to potential sexual side effects.