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Most legal cases about 5α-reductase inhibitors, drugs for hair loss and prostate issues, complain about side effects and delayed cancer diagnosis, with most lawsuits settled out of court.

Using 5-aminolevulinic acid photodynamic therapy for hair loss didn't increase hair growth but slightly reduced scalp oiliness, and it was safe with mild side effects.

Oral finasteride and dutasteride may negatively affect erectile function in rats.

Melandrium firmum extract helps mice grow hair by blocking a hair loss enzyme and changing hair growth genes.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Using finasteride for hair loss or prostate issues does not significantly raise the risk of erectile dysfunction.

The document concludes that women should not use 5-alpha-reductase inhibitors due to the risk of birth defects and limited effectiveness.

5-alpha-reductase inhibitors might help slow down low-risk prostate cancer, but their use should be cautious.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

5α-reductase inhibitors may increase the risk of depression and suicidal thoughts.

Babies were mostly born healthy from fathers who took finasteride, but some pregnancies ended early; more research is needed.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

The dutasteride nanoemulsion could improve hair loss treatment by enhancing drug penetration and retention in hair follicles.

5-Alpha reductase inhibitors are safe long-term but may be outdated for preventing less significant prostate cancer.

Bitter melon extract may help prevent hair loss and can be used in cosmetic products.

A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.

Certain drugs like Dutasteride and Finasteride might help fight SARS-CoV-2 by increasing levels of a steroid called DHEA, which can protect the heart and increase nitric oxide to counteract the virus.

Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.

Dapsone gel 5% is effective and safe for treating acne.

Minoxidil 2% is more effective for female hair loss, but botanicals have fewer side effects.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

Dutasteride is more effective than Finasteride in reducing prostate size and PSA levels, but both drugs have similar side effects.

A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.

Minoxidil and finasteride are FDA-approved treatments for male hair loss, but off-label use of oral minoxidil, dutasteride, and higher doses of finasteride and minoxidil is increasing.

β-sitosterol and brassicasterol may help treat hair loss.