1 citations,
October 2020 in “Current Drug Discovery Technologies” The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.
8 citations,
April 1991 in “European journal of endocrinology” 3α-AdiolG is a good marker for androgen activity in women with excessive hair growth and decreases with anti-androgen treatment.
64 citations,
January 1985 in “Clinical endocrinology” A combination of desogestrel and ethinyl oestradiol effectively reduces hair growth in hirsute women.
142 citations,
February 1985 in “Fertility and sterility” Spironolactone reduced hair thickness and some testosterone levels in women with excessive hair growth.
February 2024 in “Brain research bulletin” Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.
September 2022 in “Translational Andrology and Urology” Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.
12 citations,
January 1998 in “Drug safety” Finasteride helps reduce prostate size and symptoms in BPH but is less effective than terazosin and works best for larger prostates.
9 citations,
July 2011 in “The Journal of Sexual Medicine” Hair loss drugs like finasteride may cause lasting sexual and mood side effects, and more research is needed to understand these risks.
8 citations,
October 1998 in “Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology” Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.
23 citations,
December 1995 in “Archives of Dermatology” Combination therapy improves hair growth in advanced hair loss.
13 citations,
January 2008 in “Springer eBooks” June 2017 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride's sexual side effects not caused by androgen deficiency or SRD5A inhibition.
April 2021 in “Journal of evolution of medical and dental sciences” Women with PCOS have higher levels of certain androgens, which are good at predicting excess hair growth.
91 citations,
August 2014 in “Development” The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.
35 citations,
January 2018 in “Vitamins and hormones” DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.
27 citations,
July 1982 in “British Journal of Dermatology” The antiandrogen 11α-hydroxyprogesterone effectively reduces skin oil and cholesterol when applied to the skin.
10 citations,
October 2012 in “Andrology” Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.
26 citations,
March 2015 in “Phytotherapy Research” Forsythiaside-A, a natural substance, can protect against hair loss and is more effective than current treatments, potentially making it a good option for hair loss treatment.
10 citations,
December 1996 in “Fertility and Sterility” Women with acne have lower levels of a specific hormone marker than women without acne.
56 citations,
November 1993 in “Journal of The American Academy of Dermatology” Capsaicin cream quickly relieved itching in two patients with brachioradial pruritus.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” The document concludes that treatments like oral anti-androgens, minoxidil, and topical spironolactone can be effective for hair loss in men and women.
1 citations,
January 2015 in “Springer eBooks” AGA is a common hair loss disorder, and early diagnosis and treatment with minoxidil or finasteride can help reduce emotional distress.
1 citations,
November 1999 in “Hautarzt” Finasteride is not expected to be effective for treating Acne vulgaris.
April 2019 in “Journal of Investigative Dermatology” Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.
254 citations,
September 2014 in “Menopause” The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.
January 2008 in “The New England Journal of Medicine” Children receive less than half of recommended health care, and routine hormonal testing for female-pattern hair loss is unnecessary without other androgen excess symptoms.
January 2019 in “Frontiers in neurology” A nutrition program improved a young woman's concussion symptoms.
5 citations,
December 2011 in “Canadian Journal of Plastic Surgery” Hair grafts can successfully reconstruct a beard on reconstructed jaw skin, improving appearance and patient satisfaction.
July 2019 in “Journal der Deutschen Dermatologischen Gesellschaft” A mother and daughter have a rare genetic hair loss disorder with no effective treatment.