198 citations,
April 2020 in “Journal of Endocrinological Investigation” The virus was not found in the semen and urine of a man who tested positive for COVID-19.
149 citations,
June 2002 in “British Journal of Dermatology” Minoxidil works better for female hair loss, but cyproterone reduces scalp oiliness and causes menstrual issues.
139 citations,
December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
113 citations,
July 2020 in “Communications biology” Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.
82 citations,
June 2020 in “Inflammation Research” Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.
78 citations,
August 2014 in “Anais Brasileiros de Dermatologia” New vitiligo treatments focus on controlling immune damage and restoring skin color.
77 citations,
July 2020 in “European Journal of Clinical Pharmacology” Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.
75 citations,
September 2016 in “EMBO journal” PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.
74 citations,
April 2002 in “PubMed” Both oral contraceptives reduced acne effectively and had similar positive effects on skin oiliness and hair growth.
57 citations,
February 2007 in “International Journal of Cancer” A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.
51 citations,
November 2020 in “Journal of the European Academy of Dermatology and Venereology” COVID-19 infection may cause significant hair loss, but full hair recovery is likely without special treatment.
50 citations,
July 2021 in “Nature Communications” The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
50 citations,
May 2019 in “BioFactors” Pollution increases a compound in the skin that can lead to faster aging and more inflammation.
47 citations,
January 2021 in “Fertility and Sterility” COVID-19 might affect male fertility, but more research is needed to understand the full impact.
45 citations,
January 1992 in “Dermatology” Half of the patients treated with a specific drug for skin cancer experienced hair loss not related to the drug's dosage.
44 citations,
November 2009 in “Archives of Dermatology” CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.
40 citations,
June 2011 in “Journal of biological chemistry/The Journal of biological chemistry” FA2H is essential for normal fur and sebum production in mice.
40 citations,
December 2006 in “Journal of The European Academy of Dermatology and Venereology” Minoxidil helps hair regrowth in traction alopecia.
39 citations,
April 2018 in “Hormones” No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.
39 citations,
February 2011 in “The Prostate/The prostate” Some men's prostate tissues have low enzyme levels due to genetic changes, possibly affecting treatment for prostate enlargement.
38 citations,
June 2005 in “Matrix Biology” Minoxidil affects collagen-related genes, potentially helping treat fibrosis.
37 citations,
January 2002 in “British journal of dermatology/British journal of dermatology, Supplement” Apple extract called procyanidin B-2 was found to greatly increase hair growth.
35 citations,
November 2020 in “Dermatologic Therapy” Severe COVID-19 may cause hair loss, and doctors recommend supplements and topical treatments to manage it.
32 citations,
June 2013 in “Journal of Investigative Dermatology” Mice without certain skin proteins had abnormal skin and hair development.
32 citations,
December 2000 in “Phytomedicine” Apple-derived procyanidin B-2 can safely promote hair growth in men.
31 citations,
January 1989 in “Clinical and Experimental Dermatology” The study tested a hair treatment and found it can help grow hair, but won't stop baldness. It's safe and works well, but needs more testing.
30 citations,
October 2020 in “Nature Communications” Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
30 citations,
May 1999 in “Food and chemical toxicology” Procyanidin B-2 is safe to use on skin as a hair growth product.
28 citations,
January 2021 in “Skin appendage disorders” COVID-19 may cause early hair loss similar to classic temporary hair loss, with further research needed.
27 citations,
June 2013 in “Genes & development” Cav1.2 affects hair growth and could be a target for hair loss treatments.