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People with Myotonic Dystrophy type 1 are more likely to have certain skin conditions, but not more likely to get skin cancer.

A boy with Pachyonychia congenita has a confirmed gene mutation, highlighting the need for a local genetic database in India.

A 27-year-old with APS-1 showed improvement in symptoms after treatment.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.

A rare genetic mutation found in an Indian family can be detected through prenatal screening.

Tofacitinib citrate improved nail dystrophy and pain in patients with alopecia universalis without causing side effects.

Most hospitalized children with skin issues were boys, with allergic skin diseases like atopic dermatitis being most common, and treatments were usually topical.

A 12-year-old boy with twenty nail dystrophy, a condition affecting all nails, was treated conservatively due to its self-limiting nature and good prognosis.

Middle Eastern patients with epidermolysis bullosa show specific genetic mutations linked to different types of the disease.

Biotin supplements are unnecessary for most people but may help with certain conditions like biotin deficiency, brittle nails, and some hair loss.

Different nail disorders are treated by targeting their specific causes and using appropriate medications or protective measures.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

Mutations in the FOXN1 gene cause severe immune issues but don't affect hair and nails.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

HIV can cause various nail and hair disorders, important for early diagnosis and treatment.

The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.

A new mutation in the PLEC gene causes a rare condition with skin blistering, muscle weakness, and hair loss.

Skin changes like hair loss, white patches, and nail changes are common in children after bone marrow transplants, often linked to chronic rejection.

Most people with alopecia areata have nail changes, which are common but don't greatly affect their quality of life.

Alopecia areata is unpredictable, with limited treatment effectiveness, especially in severe cases.

Povidone-iodine nail solution effectively treats nail infections caused by chemotherapy.

People with Epidermolysis bullosa have many health problems including poor oral health, which is often neglected due to other medical issues.

Tofacitinib improves nail conditions in patients with severe hair loss and does not affect hair regrowth.

A man with severe hair loss saw hair and nail improvement after 10 months on tofacitinib without side effects.

Valproic acid can rarely cause reversible nail discoloration.

Skin problems are common in Lupus patients and can indicate the disease's severity, requiring specific treatments and lifestyle changes.

Laser treatment is safe and can effectively treat toenail fungus, especially when combined with other treatments if no improvement is seen after about a year.

Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.

The HoxC gene cluster and its enhancers are essential for developing hair and nails in mammals.