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Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Diagnosing PCOS in teenage girls is tricky and requires careful evaluation and management.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Hyperthyroidism can hide signs of high androgen levels in females.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.