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      learn Ketoconazole

      antifungal with some anti-androgenic benefits, often used as a shampoo

      learn Biotin

      supplement to help with hair texture and quality

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

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      community Anyone wanna try and interview the developers of RU?

      in Research/Science  83 upvotes 3 years ago
      The conversation discusses arranging an interview with the developers of RU58841 to clarify its safety and reasons for halted research, with some users expressing concerns about potential risks and others citing financial reasons for the discontinuation of studies. Specific treatments mentioned include RU58841, minoxidil, and finasteride.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  326 upvotes 1 week ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community U/joaopassos444 , HATS OFF brother !!

      in Research/Science  126 upvotes 3 years ago
      A new hair loss treatment theory beyond minoxidil and finasteride is proposed, causing mixed reactions in the community, with some members eager to explore and support it, while others call for more research and evidence.