research 078 The transmembrane protein LRIG1 regulates receptor tyrosine kinases in skin development and homeostasis
LRIG1 protein affects hair growth by regulating skin receptors, leading to hair loss when overexpressed.
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5 / 1000+ resultsresearch Receptor tyrosine kinase Kit action in skin melanocytes: is it exclusively cell autonomous?
This review discusses the roles of KIT and mast cells in skin physiology and pathology using different genetic models and reports no new clinical results; the authors suggest further exploration of KIT deficiency.
research Characterisation, genomic organisation, expression and function of the mEphA1 receptor Tyrosine Kinase
This research investigated the role of EphA1 in embryonic and adult tissues, generating mouse models suggesting potential links to skin and colon cancer, sepsis, and post-traumatic injury.
research Safety Profile of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors: A Disproportionality Analysis of FDA Adverse Event Reporting System
This study mapped the safety profile of EGFR-TKIs by analyzing FDA adverse event reports, highlighting unexpected reactions like intestinal obstruction and hypokalaemia with gefitinib and erlotinib.
research Taiwanese Dermatological Association consensus for the prevention and management of epidermal growth factor receptor tyrosine kinase inhibitor-related skin toxicities
This report presents the Taiwanese Dermatological Association's 2016 consensus on defining and managing skin toxicities from EGFR-TKI treatments, providing comprehensive guidelines for clinicians in Taiwan.
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2 / 1000+ resultscommunity Prevention of age-related beard graying in humans by the topical application of Eriodictyon angustifolium extract
Topical application of Eriodictyon angustifolium extract can prevent and reverse age-related beard graying and darken gray hair by increasing melanin production. Sterubin, a component of the extract, also promotes hair pigmentation and protects cells from DNA damage.
community Hair Restoration Log (Weekly 1.5 mm microneedling + QOD 0.5 mg Finasteride + Daily 50 mg 5% RU58841)
The user experienced side effects from daily 1 mg Finasteride and switched to 0.5 mg every other day, supplemented with creatine, tongkat ali, tribulus terrestris, vitamin D3, bromantane, l-tyrosine, and caffeine. They also use weekly 1.5 mm microneedling and daily 50 mg RU58841, except on microneedling days, to manage hair loss.
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