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GlossaryApoptotic Cells (Programmed Cell Death Cells)

cells undergoing controlled self-destruction to maintain tissue health

Apoptotic cells are cells that are undergoing apoptosis, which is a form of programmed cell death. This process is a natural and controlled way for the body to remove damaged, unnecessary, or potentially harmful cells without causing inflammation. Apoptosis is crucial for maintaining healthy tissue function and development, and its dysregulation can lead to diseases such as cancer or autoimmune disorders.

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research Effect of Extreme Consumption of Clove on the Morphology of Mice and Liver Tissue

May 2021 in “Indian journal of forensic medicine and toxicology”

Eating too much clove can cause serious liver damage.

research Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells

58 citations, January 2006 in “Skin Pharmacology and Physiology”

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

research N-Terminal Functional Domain of Gasdermin A3 Regulates Mitochondrial Homeostasis via Mitochondrial Targeting

76 citations, June 2015 in “Journal of biomedical science”

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

research Controlling Hair Loss by Regulating Apoptosis in Hair Follicles: A Comprehensive Overview

1 citations, December 2023 in “Biomolecules”

Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.

research Cell Death in Skin Function, Inflammation, and Disease

12 citations, August 2022 in “Biochemical Journal”

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

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community Fats on your Head to Stop Hair Loss?

thatdocman in Research/Science 140 upvotes 11 months ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community The Real Cause Of Androgenetic Alopecia

AccutaneEffectsInfo in Research/Science 673 upvotes 3 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community HairClone developing cell replacement treatments for Hair Loss

HairClone 6 upvotes 6 years ago

HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

lemsmurph in Treatment 97 upvotes 5 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Opinions on Scalp fibrosis and DHT?

TqmLad in Research/Science 9 upvotes 2 years ago

The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

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