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Research

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research A Novel Point Mutation in the Ligand-Binding Domain (LBD) of the Human Glucocorticoid Receptor (hGR) Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus of hGR LBD in Conferring Transactivational Activity

91 citations , May 2005 in “The Journal of Clinical Endocrinology & Metabolism”

In this study, a novel mutation in the glucocorticoid receptor gene was identified in a young woman, impairing glucocorticoid signaling and leading to generalized glucocorticoid resistance.

research Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity.

32 citations , November 2020 in “UNC Libraries”

This study identified a mutation in the steroid-binding domain of the androgen receptor gene associated with complete androgen insensitivity syndrome, impairing male sexual development due to altered androgen receptor protein function.

research Poikiloderma congenitale-an early case of rothmund-thomson's syndrome.

9 citations , January 1975 in “Munich Personal RePEc Archive (Ludwig Maximilian University of Munich)”

This report describes a case of Rothmund-Thomson type congenital poikiloderma, noting minor skin changes, hair loss, and slightly elevated lysine and cystine in the urine.

research Poikiloderma congenitale-an early case of rothmund-thomson's syndrome

7 citations , July 1975 in “Acta dermato-venereologica”

This case study reports a patient with Rothmund-Thomson type congenital poikiloderma, showing primarily skin changes and hair loss, along with slightly elevated lysine and cystine levels in urine.

research POINT OF CARE W RADIOLOGII

January 2024 in “Wiadomości Lekarskie”

This article reviews the potential applications of Point of Care procedures in radiology, discussing their ability to enhance the speed of diagnosis and treatment but does not report new results.

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Community Join

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community Any point in microneedling if I use oral minoxidil?

in Microneedling 8 upvotes 6 months ago

The conversation discusses the use of microneedling as a complementary treatment for hair loss alongside oral minoxidil and dutasteride. Opinions vary on its effectiveness, with some users supporting its benefits for hair growth and others questioning its efficacy without topical minoxidil.

community Any point in microneedling with RU?

in Microneedling 1 upvotes 1 year ago

Microneedling with RU58841 may not be necessary since RU works topically by occupying receptors before DHT binds. RU58841 is a topical anti-androgen.

community What's the point of finasteride if dutasteride exists?

43 upvotes 1 week ago

Finasteride is effective for hair loss with fewer side effects and quicker clearance compared to dutasteride, which is more potent but has a longer half-life and potentially more side effects. Users suggest starting with finasteride and considering dutasteride only if more hair retention is needed and side effects are manageable.

community at what point is it too late to start treatment? balding since 11

in Finasteride/Dutasteride 5 upvotes 2 months ago

A 20-year-old male, balding since age 11, is considering adding finasteride or dutasteride to his current minoxidil treatment. Users suggest it's not too late to start finasteride or dutasteride, as these are more effective for hormonal hair loss.

community Minoxidil may have poisoned my cat

in Minoxidil 45 upvotes 5 months ago

A user expressed concern that minoxidil might have poisoned their cat, leading to heart and lung issues, but others suggested it was unlikely due to minimal exposure. Some users recommended switching to oral minoxidil or using protective measures like a bonnet to prevent potential contact with pets.

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Learn

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learn Scalp Micropigmentation

Can scalp micropigmentation be removed? SMP can be lightened or removed with laser, usually over several sessions and at considerable cost. Removal may be incomplete and can leave scars.

learn Hair Transplant

What are the advantages of FUE hair transplant? Clinics cite faster recovery and no line scar as FUE's main advantages. It still leaves many small dot scars.
How long does a hair transplant procedure take? A hair transplant procedure typically takes 4 to 8 hours.

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Clinics

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Experts

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