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GlossaryPhosphodiesterase

enzyme that breaks down cyclic nucleotides in cells

Phosphodiesterase (PDE) is an enzyme that plays a crucial role in cellular signaling by breaking down cyclic nucleotides like cAMP and cGMP, which are molecules that transmit signals inside cells. By regulating the levels of these cyclic nucleotides, PDEs help control various physiological processes, including heart rate, inflammation, and even hair growth.

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learn Caffeine

the stimulant you know and love can be used topically to stimulate hair

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White Lupin Cluster Root Acclimation to Phosphorus Deficiency and Root Hair Development Involve Unique Glycerophosphodiester Phosphodiesterases

research White Lupin Cluster Root Acclimation to Phosphorus Deficiency and Root Hair Development Involve Unique Glycerophosphodiester Phosphodiesterases

80 citations, April 2011 in “Plant physiology”

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

research Enzymes

1 citations, November 2011 in “British journal of pharmacology”

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

research Anti-Hair Loss Effect of a Shampoo Containing Caffeine and Adenosine

May 2024 in “Journal of cosmetic dermatology”

A shampoo with caffeine and adenosine may help prevent hair loss and thicken hair.

research Novel Effect of Sildenafil on Hair Growth

16 citations, October 2018 in “Biochemical and Biophysical Research Communications”

Sildenafil, often used for erectile dysfunction, may help hair growth.

research Phosphodiesterase (PDE) Inhibitors for the Treatment of Inflammatory Skin Conditions

January 2018 in “Springer eBooks”

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

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