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Did you mean Peroxisome Proliferator-Activated Receptor γ?

GlossaryPeroxisome Proliferator-Activated Receptor Gamma

nuclear receptor protein regulating genes for fat storage and glucose metabolism

Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) is a type of nuclear receptor protein that regulates the expression of specific genes involved in fat storage, glucose metabolism, and inflammation. It plays a crucial role in the development of adipose tissue and is a target for drugs used to treat conditions like type 2 diabetes and metabolic syndrome.

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research Alopecia: Evaluation and Treatment

76 citations, July 2011 in “Clinical, Cosmetic and Investigational Dermatology”

The document concludes that proper diagnosis and FDA-approved treatments for different types of hair loss exist, but treatments for severe cases often fail and future improvements may focus on hair follicle stem cells.

Advances in Mitochondria-Centered Mechanism Behind the Roles of Androgens and Androgen Receptor in the Regulation of Glucose and Lipid Metabolism

research Advances in Mitochondria-Centered Mechanism Behind the Roles of Androgens and Androgen Receptor in the Regulation of Glucose and Lipid Metabolism

October 2023 in “Frontiers in endocrinology”

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

research Androgens and Cardiovascular Disease

658 citations, June 2003 in “Endocrine reviews”

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

research Controlling Hair Loss by Regulating Apoptosis in Hair Follicles: A Comprehensive Overview

1 citations, December 2023 in “Biomolecules”

Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.

research Clinical Translation of Microbiome Research in Alopecia Areata: A New Perspective

2 citations, May 2022 in “Cosmetics”

Further research is needed to understand how the microbiome affects hair loss in Alopecia Areata.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.