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Glossary permeation

movement of substances through a membrane or porous material

Permeation refers to the process by which a substance, such as a liquid or gas, passes through a porous material or membrane. In the context of hair and scalp treatments, permeation is crucial for understanding how active ingredients in topical products penetrate the skin and hair follicles to exert their effects. This process is influenced by factors like the molecular size of the substance, the properties of the membrane, and the presence of enhancers that facilitate deeper penetration.

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Research

5 / 1000+ results

research Ion pairs of risedronate for transdermal delivery and enhanced permeation rate on hairless mouse skin

34 citations , July 2011 in “International journal of pharmaceutics”

This study found that ion-paired solutions significantly improved the skin penetration of risedronate in hairless mice compared to risedronate alone.

research Preparation, Optimization, In vitro Evaluation and Ex vivo Permeation Studies of Finasteride loaded gel Formulations Prepared by using Response SurfaceMethodology

3 citations , September 2018 in “Current Drug Delivery”

This study found that a finasteride topical gel formulation using propylene glycol and Tween® 80 showed significantly enhanced permeation compared to a control formulation without these enhancers.

research Formulation and optimization of transfersome containing minoxidil and caffeine

32 citations , December 2017 in “Journal of Drug Delivery Science and Technology”

This study found that co-delivery of minoxidil and caffeine in transfersomes with an optimized polysorbate formulation enhanced hair length and weight in vivo.

research Perception of upper lip augmentation utilizing simulated photography

12 citations , May 2019 in “Archives of Plastic Surgery”

This study found that natural appearance was rated higher in attractiveness, perceived success, and health than simulated upper lip fillers or lifts by casual observers.

research Skin permeation of different steroid hormones from polymeric coated liposomal formulations

35 citations , October 2005 in “European journal of pharmaceutics and biopharmaceutics”

This study found that polymers significantly improved the chemical and microbial stability of steroid hormones in liposome formulations over eight weeks, with finasteride showing the highest diffusion rate.

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community Why the Brain Resists Updating Your Appearance: The Neuroscience Behind “It Happened Overnight”

6 upvotes 7 months ago

The brain resists updating its perception of gradual appearance changes, like hair loss, due to its preference for stability and reliance on an internal model. This delay in perception can make changes feel sudden once the brain finally updates its model.

community Oral Min Aging reversible?……..

11 months ago

Oral minoxidil may cause temporary facial puffiness, leading to a perception of accelerated aging, but it doesn't cause actual aging. Concerns about hair loss and treatments like minoxidil and finasteride are discussed, with suggestions to use tretinoin and sunscreen to mitigate potential side effects.

community What I hate about being told to shave my head

in Chat 258 upvotes 1 year ago

Hair loss challenges and identity issues, with opinions on using finasteride, minoxidil, and hair transplants versus accepting baldness. Some find shaving more work, while others stress personal choice and self-perception.

community Veradermics VDPHL01 Topline Results for Extended-Release Oral Minoxidil

75 upvotes 5 months ago

Extended-release oral minoxidil (VDPHL01) shows promising results for hair growth with improved safety, achieving significant hair count increases and minimal side effects compared to placebo. The treatment is designed to maintain effective concentrations while reducing side effects, making it a safer option for those who cannot tolerate standard minoxidil.

community How far back can Dutasteride regrow losses?

in Finasteride/Dutasteride 43 upvotes 10 months ago

Dutasteride can regrow hair lost up to 10 years ago for some, especially when combined with minoxidil, but results vary widely. Some users report significant regrowth, while others see no change or only maintain existing hair.

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