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    Did you mean Perifollicular Lymphocytic Infiltrate?
    GlossaryPerifollicular Lymphocytic Infiltrate

    presence of immune cells around hair follicles

    Perifollicular Lymphocytic Infiltrate refers to the presence of immune cells, specifically lymphocytes, around hair follicles. This condition is often seen in various types of hair loss disorders, such as alopecia areata, where the immune system mistakenly attacks the hair follicles, leading to hair loss.

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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 8 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  407 upvotes 2 weeks ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community Lost density 60% all over scalp in 120 days (4months)

      in Update  10 upvotes 10 months ago
      A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 7 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community Follow up appointment with Donovan.

      in Finasteride/Dutasteride  17 upvotes 1 year ago
      The user was diagnosed with DUPA and initially treated with finasteride, then switched to dutasteride which worsened their hair loss. They are now returning to finasteride and adding treatments including oral minoxidil, Proscar, Viviscal, pumpkin seed oil, LLLT, and Nizoral shampoo, hoping for hair regrowth.