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    GlossaryPapillary Dermis

    uppermost dermal layer with blood vessels and nerve endings

    The papillary dermis is the uppermost layer of the dermis, which is the thick layer of skin beneath the outer epidermis. It contains thin collagen fibers, small blood vessels, and nerve endings, playing a crucial role in supplying nutrients to the epidermis and regulating temperature. This layer also contributes to the skin's tactile properties and helps in wound healing.

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      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn SCUBE3

      a signaling molecule from dermal papilla cells being actively researched

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

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      community Comprehensive Microneedling Guide

      in Microneedling  287 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community Vitamin C and hair growth PH levels

      in Product  29 upvotes 3 years ago
      The conversation is about using vitamin C and Magnesium L-Threonate for hair growth by reducing DHT binding to dermal papilla cells. The original post about vitamin C's pH levels and sebum control was possibly removed by a moderator.

      community Summary of Procapil video by Haircafe

      in Minoxidil  1 upvotes 1 week ago
      Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 11 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.