April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”
Developing hair follicles form from ring-shaped patterns, with future stem cells originating from the outerring, not the upper layers, as previously thought.
The conversation discusses the timing of applying Minoxidil and finasteride after microneedling. Opinions vary, with some suggesting immediate application and others recommending waiting to avoid skin irritation.
IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.
Iontophoresis and sonophoresis can enhance drug delivery into the scalp. Combining these methods may improve the effectiveness of topical treatments like dutasteride and certain peptides.
The efficacy of microneedling for hair regrowth as either a stand-alone therapy or adjunct to Minoxidil, and whether Tretinoin is a safer and more effective option. Replies include personal accounts from users who have had success with microneedling in combination with minoxidil and peptide serums, as well as considerations of technique, depth, and potential scarring.
The potential effectiveness of topical dutasteride, as well as other hair loss treatments such as finasteride, RU58841, minoxidil, and various vitamins. Experiences from users who have used these treatments were shared.