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    Glossary oncogene

    gene that can cause cancer when mutated or overexpressed

    An oncogene is a type of gene that, when mutated or expressed at high levels, can transform a normal cell into a cancerous one. In simpler terms, it's like a switch that, when turned on incorrectly, can lead to uncontrolled cell growth and potentially cancer. For professionals, oncogenes are often derived from proto-oncogenes, which are normal genes involved in cell growth and division, but become harmful when altered.

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    Research 10 of 626

    1. Oncogenes and morphogens: intricacies of targeted therapy in cutaneous basal cell carcinoma British Journal of Dermatology · 2017
    2. Molecular mechanisms of viral oncogenesis in humans Nature Reviews Microbiology · 2018 · 141 citations
    3. The E6/E7 oncogenes of human papilloma virus and estradiol regulate hedgehog signaling activity in a murine model of cervical cancer Experimental Cell Research · 2019 · 9 citations
    4. Iperplasia Collaterale Nella Oncogenesi Sperimentale Del Ratto: Rilievi in corso di trattamento con Vitamina A Tumori Journal · 1961
    5. The HPV16 oncogenes cause aberrant stem cell mobilization Virology · 2013 · 23 citations
    6. Human Papillomavirus E6/E7 Oncogenes Promote Mouse Ear Regeneration by Increasing the Rate of Wound Re-epithelization and Epidermal Growth Journal of Investigative Dermatology · 2008 · 19 citations
    7. Expression of E6 and E7 papillomavirus oncogenes in the outer root sheath of hair follicles extends the growth phase and bypasses resting at telogen. PubMed · 2000 · 10 citations
    8. Expression of hair keratins in the adult nail unit: an immunohistochemical analysis of the onychogenesis in the proximal nail fold, matrix and nail bed British Journal of Dermatology · 2004 · 110 citations
    9. Type XVII collagen suppresses interfollicular epidermal proliferation in neonatal and aged skin, and helps rejuvenate epidermis 2017
    10. Author response: Type XVII collagen coordinates proliferation in the interfollicular epidermis 2017
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