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    Did you mean Nonsteroidal Inhibitors?
    GlossaryNonsteroidal Inhibitors

    compounds that block biological processes without using steroids

    Nonsteroidal inhibitors are compounds that block specific biological processes without using steroid structures. In the context of hair and alopecia, these inhibitors can target enzymes or pathways involved in hair loss, such as 5-alpha-reductase, which converts testosterone to dihydrotestosterone (DHT), a hormone linked to hair thinning and loss.

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      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn Bicalutamide

      a nonsteroidal anti-androgen, most commonly used orally for women

      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

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      community So we’re just ok with taking a research chemical now?

      in Treatment  179 upvotes 4 years ago
      The conversation discusses the use of RU58841, a non-FDA approved research chemical for hair loss, with mixed opinions on its safety and effectiveness. Some users are willing to try it as a last resort after other treatments like Minoxidil and Finasteride failed, while others express concerns about potential long-term side effects and lack of official research.

      community Finasteride doubled my testosterone & estrogen

      in Chat  265 upvotes 2 weeks ago
      Finasteride increased testosterone and estrogen, stopped hair loss, and promoted regrowth. Users discussed side effects like libido changes and considered adding minoxidil and aromatase inhibitors.

      community Methods Of Staying Safe On Ru58841 - My 2 Cents

      in Research/Science  22 upvotes 10 months ago
      RU58841 is used topically to prevent hair loss by blocking DHT, with suggestions to drink grapefruit juice, take breaks, avoid microneedling, and use lower concentrations to reduce side effects. Users discuss applying it at night to minimize systemic absorption.

      community Pyrilutamide phase III clinical trial results released

      in Research/Science  31 upvotes 1 year ago
      Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.