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Glossary Metabolic Dysfunction

abnormalities in body's metabolic processes affecting energy conversion

Metabolic dysfunction refers to abnormalities in the body's metabolic processes, which can lead to issues like insulin resistance, obesity, and abnormal lipid levels. These disruptions can affect how the body converts food into energy and how it manages essential functions, potentially contributing to conditions such as type 2 diabetes and cardiovascular disease.

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Research

5 / 1000+ results

research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men

31 citations , January 2017 in “Advances in Experimental Medicine and Biology”

This review discusses the negative health impacts of testosterone deficiency and the potential adverse effects of 5α-reductase inhibitors, emphasizing the need for patient-physician discussions regarding these treatments.

research Role of S-Palmitoylation by ZDHHC13 in Mitochondrial function and Metabolism in Liver

59 citations , May 2017 in “Scientific reports”

This study found that ZDHHC13 deficiency in mice is associated with abnormal liver function, lipid metabolism issues, and impaired mitochondrial function, highlighting ZDHHC13's regulatory role in liver metabolism.

research TCF/Lef1-Mediated Control of Lipid Metabolism Regulates Skin Barrier Function

22 citations , September 2011 in “Journal of Investigative Dermatology”

This study found that impaired TCF/Lef1 signaling in mice leads to significant skin barrier defects due to altered lipid metabolism and epidermal differentiation.

research GLP-1 Receptor Analogs: Evidence Linking to Effect on Metabolic and Reproductive Functions in Patients with PCOS and Obesity

3 citations , July 2025 in “Obesity Facts”

This review examines how GLP-1 receptor agonists might impact metabolic and reproductive outcomes in polycystic ovary syndrome, but it reports no new clinical findings and highlights the need for further research.

research Vitamin D metabolism and function in the skin

185 citations , June 2011 in “Molecular and cellular endocrinology”

This review discusses the regulation and function of vitamin D and its receptor in skin cells, highlighting their roles in processes such as proliferation inhibition, differentiation, and innate immunity, but reports no new results.

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Community Join

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community The mechanism of androgenic alopecia

36 upvotes 11 months ago

DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

2 upvotes 1 year ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

in Research 413 upvotes 1 year ago

Treating androgenic alopecia with minoxidil, finasteride, and antiandrogens, alongside exercise, cryotherapy, and natural substances to stimulate cold receptors for better hair growth. The method focuses on enhancing treatment effectiveness by considering environmental and behavioral factors and the role of cold receptors and muscle stress.

community Could male-pattern baldness have a secondary photobiological function? The Solar Window Hypothesis

11 upvotes 1 month ago

Male-pattern baldness might increase UVB exposure on the scalp, potentially affecting vitamin D and skeletal health. The hypothesis is debated, with some seeing it as a minor benefit in specific contexts.

community Dear Dut users,have you noticed any metabolic changes with use of the drug?

6 upvotes 1 year ago

Dutasteride users have mixed results in hair loss treatment, with some experiencing improvements and others worsening. Some report metabolic changes like weight gain or diabetes, while others have no significant side effects.

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Learn

3 / 7 results

learn Vitamin D

Vitamin made in the skin from sunlight, also taken as a supplement

learn Melatonin

Hormone that regulates sleep, sold as a supplement

learn Neem Oil

Oil from the neem tree, used in traditional remedies

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Clinics

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Hair Loss Treatments
True North MetabolicWoolwich, ON · CA

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