1 citations
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February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” The study investigated the impact of fiber diameter in aligned electrospinning membranes on skin wound healing. Membranes with a diameter of 319±100 nm (A300) were found to significantly enhance cell proliferation, spreading, and skin wound healing, including epithelization, vascularization, and hair follicle regeneration. The molecular mechanism involved A300 promoting macrophage transformation to reparative phenotypes with increased expression of IL10 and TGFβ, which facilitated epidermal cell migration through the secretion of matrix metalloproteinases 12 (MMP12). These findings suggested that A300 membranes could be a promising candidate for guided skin regeneration applications.
1 citations
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November 2024 in “Life” Desmodesmus pannonicus water extract may help reduce skin pigmentation, heal wounds, and promote hair growth.
21 citations
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May 2016 in “Experimental and Therapeutic Medicine” MMP-2 and MMP-9 help hair grow, while their inhibitors peak when hair growth slows.
9 citations
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August 2005 in “Archives of Dermatological Research” Scalp dermal papilla and fibrous sheath cells have different MMP expression than scalp dermal fibroblasts.
57 citations
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March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.