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5 / 11 resultslearn Rapamycin
mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth
learn Dutasteride
Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
learn Melatonin
hormone commonly taken for sleep aid has some topical benefits for hair
learn Baricitinib
JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases
Research
5 / 1000+ resultsresearch Major Histocompatibility Complex Class I Chain-Related Gene A Polymorphisms and Extended Haplotypes Are Associated with Familial Alopecia Areata
Certain genetic markers, especially the MICA gene, are linked to alopecia areata.
research Epidermal Growth Factor Receptor/Mitogen-Activated Kinase Inhibitor Treatment Induces a Distinct Inflammatory Hair Follicle Response That Includes Collapse of Immune Privilege
EGFRi/MEKi treatments cause hair follicles to lose some immune protection, leading to inflammation.
research Case of Alopecia Induced by Sorafenib, Possible Mechanism Similar to Alopecia Areata
Sorafenib may cause hair loss in a way similar to alopecia areata.
research Alopecia Areata Is Associated With MICA and an Extended HLA Haplotype
Certain genes are linked to the risk of developing Alopecia Areata.
research An In Silico Approach to the Identification of Potential Proteomic and Genomic Diagnostic Biomarkers for Primary Cicatricial Alopecia
The study utilized an in silico approach to identify potential proteomic and genomic biomarkers for primary cicatricial alopecia (PCA), a condition with unclear pathogenesis. By analyzing gene and protein interactions, the research highlighted the involvement of the major histocompatibility complex (MHC) in lichen plano-pilaris (LPP) and frontal fibrosing alopecia (FFA), and the roles of matrix metalloproteinases (MMPs) in central centrifugal alopecia (CCCA) and LPP. The study found strong interactions among genes and proteins, suggesting their biological relevance in PCA pathogenesis. These findings could guide future research into drug targets for PCA treatment, although the clinical application of proteomics and genomics in dermatology was still emerging at the time.
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5 / 1000+ resultscommunity Major body hair loss from Finasteride (Also, just started oral minoxidil this week.)
User experienced significant body hair loss from Finasteride and started oral Minoxidil to address crown thinning. Their current regimen includes 1mg Finasteride, 2.5mg Minoxidil, Biotin, Vitamin D, Zinc, Iron, and ketoconazole shampoo.
community Experiencing Major Shed After Switching to Dutasteride and Moving Stress—Advice Needed
Switching from finasteride and topical minoxidil to dutasteride and oral minoxidil caused a major hair shed, exacerbated by moving stress. Dutasteride may take months to fully integrate, and adding finasteride might help with hair protection during this transition.
community 31M - major hair shedding after weight loss + stopping vitamins — help!
A 31-year-old male experienced hair shedding after rapid weight loss and stopping vitamins, despite using minoxidil and other supplements. He is considering Saw Palmetto and Pumpkin Seed Oil instead of finasteride due to trying for kids, and is concerned about high ferritin and DHEAS levels.
community (37M) Major progress! One side significantly better than the other, but I have a theory.
A 37-year-old man reports significant hair regrowth using a regimen of topical minoxidil, oral finasteride, derma rolling, and saw palmetto shampoo, but notices uneven progress between the sides of his head. He theorizes that sleeping on one side might affect hair growth, but others suggest it could be unrelated to sleeping habits.
community 26 months progress – major improvement and stability
A 36-year-old achieved significant hair improvement and stability over 26 months using oral finasteride, minoxidil foam, microneedling, and ketoconazole shampoo, with no side effects. Patience and consistency were crucial for increased hair density and reduced shedding.