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    Did you mean Major Histocompatibility Complex?
    GlossaryMajor Histocompatibility Complex

    set of genes crucial for immune system's pathogen recognition

    The Major Histocompatibility Complex (MHC) is a set of genes that play a crucial role in the immune system by helping the body recognize and respond to foreign substances. These genes produce proteins found on the surface of cells that present fragments of pathogens to immune cells, triggering an immune response.

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      community RU58841 and some major questions?

      in Treatment  6 upvotes   7 months ago
      A user is asking about the effectiveness and dosage of RU58841 for hair loss, comparing it to Minoxidil and discussing its long-term use alongside Finasteride. They plan to use RU58841 and Finasteride for several years before potentially switching to GT20029.

      community 22 years since the last major development

      in Technology  51 upvotes   3 years ago
      The conversation discusses the lack of significant advancements in hair loss treatments since the introduction of finasteride 22 years ago, with many expressing frustration over the failure of new projects and skepticism about future developments. Some users mention hair transplants and other potential alternatives like Alfatradiol and Fluridil, but acknowledge finasteride's dominance in the market due to its effectiveness and affordability.

      community 24 M diffuser, 3 months major progress

      in Update  7 upvotes   6 years ago
      A 24-year-old male saw major hair regrowth progress in 3 months using Nizoral, minoxidil, finasteride, vitamins, and dermarolling. After 7 months, he switched to liquid minoxidil, oral finasteride, and stopped dermarolling.

      community First 3 months on Propecia

       6 upvotes   8 years ago
      The user experienced no major negative symptoms from Propecia but noted ball throbbing and emotional inertia. They also used Minoxidil and observed increased focus and prolonged moods.

      community My Testosterone results before and after Finasteride

      in Update  149 upvotes   2 years ago
      Finasteride significantly increased testosterone levels for the user, with no major side effects except watery semen, which was resolved with zinc supplements. The user's hairline stopped receding and slightly improved.

      community 1 Year update with a lot of pics (you have been warned)

      in Update  55 upvotes   6 years ago
      The user has been taking finasteride for a year, experiencing no major side effects except watery semen, and has noticed healthier, thicker hair with some regrowth but mostly maintenance. They also use Nizoral for dandruff, take supplements like D3 and fish oil, and plan to continue finasteride while waiting for new treatments.

      community 2 Years Results - 0.5mg Fin Only.

      in Progress Pictures  442 upvotes   2 months ago
      A user shared their 2-year results using only 0.5mg finasteride for hair loss, noting improvement after 8-10 months and no major shedding or side effects. They are 34 years old and have avoided using Minoxidil.

      community How important is microneedling (dermarolling)?

      in Microneedling  9 upvotes   3 months ago
      A user has been using oral finasteride and minoxidil without significant hair regrowth and is questioning the effectiveness of adding microneedling to their routine. Another user suggests microneedling can help with topical treatments but doesn't see it as a major factor in improving hair loss.

      community 6 months only finasteride 1.25 mg

      in Progress Pictures  1368 upvotes   4 months ago
      After six months on 1.25 mg of finasteride, a user reports significant hair regrowth with no major shedding and uses a local brand of the medication. Some users inquire about side effects and brand differences, while others share their own experiences and concerns about hair loss treatment.

      community Hypertrichosis Photos from Oral Minoxidil

      in Progress Pictures  266 upvotes   5 months ago
      A user shared their experience with oral minoxidil and finasteride for hair loss, taking 7.5mg of minoxidil and experiencing excessive hair growth all over their body without major side effects. Some users suggested lower doses for safety, while others shared their own experiences with hair growth in different areas and side effects.

      community My barber noticed my progress 😁

      in Update  207 upvotes   6 months ago
      A user's barber noticed significant improvement in their hair thickness after they started using 2.5mg Minoxidil since August 2023 and 1mg Finasteride daily since September 2023. The user has experienced some headaches when missing Minoxidil doses but has not noticed major side effects.

      community Progress: 0.5mg finasteride + 2.5 mg oral minoxidil

      in Progress Pictures  431 upvotes   1 year ago
      This user uses a combination of finasteride and oral minoxidil to treat hair loss, and reports that the treatment has had an impact on his growth without any major side effects. He also shares advice on how to obtain the necessary medications in certain countries.

      community 9 months on treatment

      in Treatment  9 upvotes   5 years ago
      A 30-year-old from Mexico shares his 9-month experience using finasteride, ketoconazole shampoo, and minoxidil for hair loss, reporting no major side effects except for hair dryness. He advises using conditioner and coconut oil to minimize hair breakage and encourages others to try these treatments while seeking help if hair loss affects mental health.

      community Fin update

      in Finasteride  6 upvotes   7 years ago
      User took 1mg finasteride daily and 2% ketoconazole weekly for 5 months, seeing slight hairline regrowth and no major side effects except temporary dry eyes. They encourage others to try finasteride despite negative stories online.

      community My progress after 13 months on dutasteride and Minoxidil

      in Progress Pictures  678 upvotes   8 months ago
      A user shared their positive experience with hair regrowth after 13 months of using dutasteride and minoxidil, noting improved self-confidence and physical fitness. They reported noticeable results after 2 months, with significant improvement by 7-8 months, and no major side effects.

      community Help Me I used too much essential oils.

      in Product  7 upvotes   9 months ago
      A user mixed peppermint, rosemary, and castor oil and applied it to their scalp, causing excessive hair shedding. They're concerned about permanent hair loss, while another user shared their experience of using undiluted rosemary oil without any major issues.

      community My Pyrilutamide Experience Update 2, Part 1

      in Update  64 upvotes   1 year ago
      The user's experience taking Pyrilutamide, a drug for hair loss treatment, and their use of it in combination with other treatments such as Minoxidil, Finasteride and RU58841. They have experienced positive results so far with no major side effects.

      community 3 months progress on dutasteride and oral minoxidil

      in Progress Pictures  61 upvotes   2 years ago
      EdgeLord19941's progress with hair loss medication, which includes 0.5mg dutasteride daily, 5mg oral minoxidil daily and microneedling with an electronic pen once every 7-14 days at 1.5mm. There have been positive results reported within 3 months of following this regimen with no major side effects.

      community It’s crazy how it’s 2018 and the only hair loss treatments we have feature undesirable side effects and/or aren’t even effective for many people.

       136 upvotes   6 years ago
      Hair loss treatments, including minoxidil, dermarolling, finasteride, dutasteride, hair transplants, hair systems, and shaving the head. The conversation covers various opinions on these treatments and mentions possible side effects as well as alternatives like wigs, vitamins, and lifestyle changes. The post expresses disappointment that there has been no major breakthrough in the field of hair loss treatments despite decades of research.

      community Research about RU58841 /Why it was stopped

      in Research/Science  29 upvotes   3 years ago
      RU58841 showed promise for treating androgenic alopecia but research was halted due to financial and organizational changes. There were no significant safety concerns reported in human trials.