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    Did you mean Major Histocompatibility Complex?
    Glossary Major Histocompatibility Complex

    set of genes crucial for immune system's pathogen recognition

    The Major Histocompatibility Complex (MHC) is a set of genes that play a crucial role in the immune system by helping the body recognize and respond to foreign substances. These genes produce proteins found on the surface of cells that present fragments of pathogens to immune cells, triggering an immune response.

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      research Distribution of major histocompatibility antigens in normal skin

      68 citations , December 1983 in “British Journal of Dermatology”
      This study found HLA and beta 2-microglobulin antigens in various skin structures, with specific localization patterns in keratinocytes and hair follicle components, but not in eccrine or apocrine glands.
      Exploring the Role of MicroRNAs in Alopecia Areata

      research 875 Exploring the role of microRNAs in alopecia areata

      April 2017 in “Journal of Investigative Dermatology”
      This study found that miR-486 and miR-451 levels were reduced in alopecia areata-affected skin, and delivering their mimics to mice mitigated symptoms by reducing inflammation and immune activity.
      Possible Role of ILC1 in the Pathogenesis of Alopecia Areata

      research 516 Possible role of ILC1 in the pathogenesis of alopecia areata (AA)

      3 citations , April 2019 in “˜The œjournal of investigative dermatology/Journal of investigative dermatology”
      This research suggests that innate lymphoid cells type 1 (ILC1) may contribute to the development of alopecia areata, alongside CD8+ T cells, by disrupting hair follicle immune privilege and promoting features of the disease.

      research Nail Involvement inAutoimmune Bullous Disorders

      January 2011
      This study found that the nail immune system is similar to the hair follicle immune system, with both showing a relative "immune privilege" that may protect against autoimmunity.
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