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Did you mean Macrophage Polarization?

GlossaryMacrophage Polarization

process where immune cells change roles based on signals

Macrophage polarization refers to the process by which macrophages, a type of immune cell, change their functional state in response to different signals in their environment. They can adopt a pro-inflammatory state (M1) to fight infections or a healing state (M2) to repair tissues. This ability to switch roles is crucial for maintaining balance in the immune system and is important in conditions like infections, cancer, and autoimmune diseases.

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research Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa

22 citations, August 2021 in “Frontiers in medicine”

Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

Human Adipose Tissue-Derived Small Extracellular Vesicles Promote Soft Tissue Repair Through Modulating M1-To-M2 Polarization Of Macrophages

research Human Adipose Tissue-Derived Small Extracellular Vesicles Promote Soft Tissue Repair Through Modulating M1-To-M2 Polarization Of Macrophages

2 citations, April 2023 in “Stem Cell Research & Therapy”

Tiny fat-derived particles can help repair soft tissues by changing immune cell types.

research 26SCS-Loaded SilMA/Col Composite Sponge with Well-Arranged Layers Promotes Angiogenesis-Based Diabetic Wound Repair by Mediating Macrophage Inflammatory Response

April 2024 in “Molecules/Molecules online/Molecules annual”

The composite sponge helps heal diabetic wounds by reducing inflammation and promoting new blood vessel growth.

ADM Scaffolds Generate a Pro-Regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1

research ADM Scaffolds Generate a Pro-Regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1

17 citations, June 2018 in “Frontiers in Physiology”

ADM scaffolds help skin heal by promoting a healing-type immune response.

research Dual-Action Icariin-Containing Thermosensitive Hydrogel for Wound Macrophage Polarization and Hair Follicle Neogenesis

6 citations, June 2022 in “Frontiers in Bioengineering and Biotechnology”

The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.

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community Just to show you the superiority of dutasteride over finasteride (it's huge)

in Research/Science 58 upvotes 5 months ago

Dutasteride is shown to be significantly more effective than finasteride for treating male androgenic alopecia. Users discuss the difficulty of obtaining dutasteride in some countries and share personal experiences with its effectiveness and side effects.

community 32 M 1 year anniversary on Fin

in Progress Pictures 153 upvotes 7 months ago

A 32-year-old man has been using topical minoxidil for 11 years and oral finasteride for 1 year, along with a dermaroller, and is happy with his hair regrowth progress without experiencing side effects. Commenters are impressed and some are considering starting finasteride after seeing his results.

community (20 M) 1 Year of Progress Fin and Min

in Progress Pictures 1227 upvotes 1 year ago

A 20-year-old man shared his one-year progress using finasteride and minoxidil for hair loss. He experienced no side effects, saw results within weeks, and despite occasional shedding, his hair grew back thicker and in previously bald spots.

community 3 months of hair treatment! I think I’m hyper responsive to my treatment. Finasteride, biotin pills, derma roller with rosemary/jojoba oil applied after, coffee in the morning for caffeine . No diet or alcohol consumption changes.

in Progress Pictures 491 upvotes 11 months ago

The user reports significant hair regrowth after three months using finasteride, biotin pills, a derma roller with rosemary/jojoba oil, and drinking coffee, despite an initial increase in hair shedding. Other users share varied results with similar treatments, with some not experiencing improvements.

community 1.5 years fin plus almost 3 years min, I think I’ve definitely made progress but I’m still not where I want to be, advice?

in Progress Pictures 130 upvotes 10 months ago

The user has been using finasteride for 1.5 years and minoxidil for almost 3 years for hair loss, and has seen some maintenance of hair but not significant regrowth. Suggestions from others include switching to dutasteride, trying oral minoxidil, and considering microneedling or hair fibers for better appearance.

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