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    Did you mean Macrophage Polarization?
    Glossary Macrophage Polarization

    process where immune cells change roles based on signals

    Macrophage polarization refers to the process by which macrophages, a type of immune cell, change their functional state in response to different signals in their environment. They can adopt a pro-inflammatory state (M1) to fight infections or a healing state (M2) to repair tissues. This ability to switch roles is crucial for maintaining balance in the immune system and is important in conditions like infections, cancer, and autoimmune diseases.

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    Research 30 of 1000+

    1. Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa Frontiers in medicine · 2021 · 22 citations
    2. Cedrol from Platycladus orientalis (L.) Franco regulates M1/M2 polarization of macrophages and promotes hair regeneration Journal of Ethnopharmacology · 2026
    3. Human adipose tissue-derived small extracellular vesicles promote soft tissue repair through modulating M1-to-M2 polarization of macrophages Stem Cell Research & Therapy · 2023 · 2 citations
    4. Intrinsic ROS Drive Hair Follicle Cycle Progression by Modulating DNA Damage and Repair and Subsequently Hair Follicle Apoptosis and Macrophage Polarization Oxidative Medicine and Cellular Longevity · 2022 · 20 citations
    5. Sustained Exosome‐Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins and MiRNAs, and Sustained Release Formulation Small · 2022 · 40 citations
    6. DcR3 reprograms macrophage plasticity to promote wound healing and hair regeneration Journal of Dermatological Science · 2026
    7. Spatiotemporal regulation of acute wound healing by the NLRP3 inflammasome: dual roles in macrophage-fibroblast chemotaxis and phenotype during wound repair Burns & Trauma · 2026
    8. 26SCS-Loaded SilMA/Col Composite Sponge with Well-Arranged Layers Promotes Angiogenesis-Based Diabetic Wound Repair by Mediating Macrophage Inflammatory Response 2024
    9. <em>Flammulina velutipes</em> polysaccharide boosts the anti-tumor immunity by reversing M1/M2 polarization through TLR4/NF-κB activation Food Science and Human Wellness · 2026
    10. Tibial cortex transverse transport accelerates diabetic wound healing via systemic mobilization of non-classical monocytes Bone and Joint Research · 2026
    11. All‐Natural Immunomodulatory Bioadhesive Hydrogel Promotes Angiogenesis and Diabetic Wound Healing by Regulating Macrophage Heterogeneity Advanced Science · 2023 · 254 citations
    12. The impact of biomaterial characteristics on macrophage phenotypes in tissue engineering: a review Plastic and Aesthetic Research · 2025 · 6 citations
    13. ADM Scaffolds Generate a Pro-regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1 Frontiers in Physiology · 2018 · 17 citations
    14. Macrophages are necessary for skin regeneration during tissue expansion Journal of Translational Medicine · 2019 · 44 citations
    15. CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation Journal of Cellular and Molecular Medicine · 2025 · 3 citations
    16. Nanofiber-mediated sequential photothermal antibacteria and macrophage polarization for healing MRSA-infected diabetic wounds Journal of Nanobiotechnology · 2021 · 18 citations
    17. M-CSF-Stimulated CD11b+ Myeloid Cells Induce Alopecia Areata in C3H/HeJ Mice Research Square (Research Square) · 2021
    18. Dual-Action Icariin-Containing Thermosensitive Hydrogel for Wound Macrophage Polarization and Hair-Follicle Neogenesis Frontiers in Bioengineering and Biotechnology · 2022 · 6 citations
    19. Effect of injectable calcium alginate-amelogenin hydrogel on macrophage polarization and promotion of jaw bone osteogenesis 2023
    20. Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization Cell Metabolism · 2014 · 222 citations
    21. Tannic acid-modified MoS 2 /silk fibroin hydrogel photothermal antibacterial synergistic macrophage M2 polarization regulation for the treatment of diabetic ulcers Materials Technology · 2026
    22. Xinyang tablet ameliorates sepsis-induced myocardial dysfunction by regulating Beclin-1 to mediate macrophage autophagy and M2 polarization through LncSICRNT1 targeting E3 ubiquitin ligase TRAF6 Chinese Medicine · 2023 · 6 citations
    23. 3D bioprinting of engineered exosomes secreted from M2-polarized macrophages through immunomodulatory biomaterial promotes in vivo wound healing and angiogenesis Bioactive Materials · 2024 · 22 citations
    24. Macrophage Related Chronic Inflammation in Non-Healing Wounds Frontiers in Immunology · 2021 · 228 citations
    25. Activation of Astrocytes &lt;i&gt;in Vitro&lt;/i&gt; by Macrophages Polarized with Keratin Biomaterial Treatment Open journal of regenerative medicine · 2016 · 6 citations
    26. Recombinant Human Annexin A5 Ameliorates Localized Scleroderma by Inhibiting the Activation of Fibroblasts and Macrophages Pharmaceutics · 2025
    27. Epigenetic orchestration of RNA m<sup>6</sup>A methylation in wound healing and post-wound events International Journal of Biological Sciences · 2025 · 3 citations
    28. Smart hydrogel dressings for advanced wound healing: from biomaterial design to microenvironment modulation Frontiers in Materials · 2026
    29. Immune Microenvironment of Hair Follicles in Tumor Immunotherapy ImmunoTargets and Therapy · 2026
    30. Programmed nanozyme hydrogel enabling spatiotemporal modulation of wound healing achieves skin regeneration after biofilm infection Journal of Nanobiotechnology · 2025