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Did you mean Macrophage Polarization?

GlossaryMacrophage Polarization

process where immune cells change roles based on signals

Macrophage polarization refers to the process by which macrophages, a type of immune cell, change their functional state in response to different signals in their environment. They can adopt a pro-inflammatory state (M1) to fight infections or a healing state (M2) to repair tissues. This ability to switch roles is crucial for maintaining balance in the immune system and is important in conditions like infections, cancer, and autoimmune diseases.

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community Just to show you the superiority of dutasteride over finasteride (it's huge)

in Research/Science 58 upvotes 5 months ago

Dutasteride is shown to be significantly more effective than finasteride for treating male androgenic alopecia. Users discuss the difficulty of obtaining dutasteride in some countries and share personal experiences with its effectiveness and side effects.

community 32 M 1 year anniversary on Fin

in Progress Pictures 153 upvotes 7 months ago

A 32-year-old man has been using topical minoxidil for 11 years and oral finasteride for 1 year, along with a dermaroller, and is happy with his hair regrowth progress without experiencing side effects. Commenters are impressed and some are considering starting finasteride after seeing his results.

community (20 M) 1 Year of Progress Fin and Min

in Progress Pictures 1227 upvotes 1 year ago

A 20-year-old man shared his one-year progress using finasteride and minoxidil for hair loss. He experienced no side effects, saw results within weeks, and despite occasional shedding, his hair grew back thicker and in previously bald spots.

community 3 months of hair treatment! I think I’m hyper responsive to my treatment. Finasteride, biotin pills, derma roller with rosemary/jojoba oil applied after, coffee in the morning for caffeine . No diet or alcohol consumption changes.

in Progress Pictures 491 upvotes 11 months ago

The user reports significant hair regrowth after three months using finasteride, biotin pills, a derma roller with rosemary/jojoba oil, and drinking coffee, despite an initial increase in hair shedding. Other users share varied results with similar treatments, with some not experiencing improvements.

community 1.5 years fin plus almost 3 years min, I think I’ve definitely made progress but I’m still not where I want to be, advice?

in Progress Pictures 130 upvotes 10 months ago

The user has been using finasteride for 1.5 years and minoxidil for almost 3 years for hair loss, and has seen some maintenance of hair but not significant regrowth. Suggestions from others include switching to dutasteride, trying oral minoxidil, and considering microneedling or hair fibers for better appearance.

community 9 month hair recovery update.. Using minoxidil once a day, 1mg of finasteride once a day.. Alpecine shampoo, coconut oil, a multivitamin a day and plenty of water.. This is not a hair transplant, I'm not rich.. and I can't afford to pay my bills yet alone get transplantation surgery haha 👍😂✌️

in Progress Pictures 44 upvotes 3 years ago

A user shared their 9-month hair recovery progress using minoxidil, finasteride, Alpecine shampoo, coconut oil, a multivitamin, and plenty of water. Replies praised the significant improvement from NW3 to NW2 with good density.

community If you can give one advice to your younger self then what that would be?

in Research/Science 2677 upvotes 4 months ago

Users discussed hair loss treatments, specifically minoxidil and finasteride. They shared personal experiences and advice on starting these treatments early.

community Progress update: Fin 6.5 months, min 7.5 months, just switched to oral

in Progress Pictures 553 upvotes 1 year ago

A user's progress with hair loss treatment using finasteride and minoxidil, with additional advice from other users about the use of dutasteride, LLLT (irestore hat), and Dr pen microneedling.

community 5 months progress oral min and fin

in Progress Pictures 377 upvotes 5 months ago

A user shared 5 months of progress using 1mg finasteride and 2.5mg minoxidil, showing before and after pictures. Other users complimented the results and discussed their own experiences with similar treatments.

community Is regrowth on an androgen receptor blocker possible?

in Chat 12 upvotes 7 months ago

RU and Pyri block androgen receptors to prevent hair loss but may also hinder hair regrowth since they prevent testosterone, which can stimulate hair growth, from binding to these receptors. The user is questioning if this understanding is correct.

community Finasteride is ****ing magical

in Update 314 upvotes 1 month ago

Finasteride has led to significant hair regrowth for some users, with noticeable improvements in two months, but side effects like erectile dysfunction have caused some to stop using it. Some users combine finasteride with minoxidil and other supplements, despite concerns about side effects.

community 3.5 months progress on only oral finasteride 1.25mg daily

in Update 455 upvotes 3 months ago

User shared 3.5 months progress on oral finasteride 1.25mg daily with no side effects. Other users commented on the effectiveness and shared their experiences.

community Anyone used CB-03-01 (clascoterone), is it worth it, too risky??

in Research/Science 2 upvotes 6 months ago

The user experienced side effects from low-dose topical finasteride and is considering using clascoterone (CB-03-01) despite concerns about its risks and cost. They seek advice on its effectiveness and potential side effects compared to other treatments like alfatradiol and fluridil.

community 2 years on .5mg Finasteride/day

in Progress Pictures 120 upvotes 6 months ago

A user shared progress pictures after 2 years on 0.5mg finasteride daily, also using minoxidil, showing significant hair improvement. The user noted their hairline is almost fully recovered.

community 3 month progress on Minoxidil 5% only.

in Is this regrowth? 1033 upvotes 6 months ago

A user is pleased with their hair regrowth after 3 months using Minoxidil 5%. They plan to start Finasteride upon returning home, and others discuss the importance of consistency and patience with hair loss treatments.

community 3 months 7 days fin 0.5mg /Min and derma

in Is this regrowth? 131 upvotes 8 months ago

The user has been using finasteride (0.5mg), minoxidil (5% foam), dermarolling, and rosemary oil for 3 months, noticing baby hairs and some shedding. Advice given includes continuing the current treatment, considering additional treatments, and potentially increasing the finasteride dose.

community 30M 3.5 months on oral fin and topical min.

in Is this regrowth? 91 upvotes 1 year ago

User reports 3.5 months on oral finasteride and topical minoxidil for hair loss. They see improvement in crown area and thicker hair, trusting the process.

community 33M, Fin only, If I can then so can you! 4 years of progress on my hairline.

in Finasteride/Dutasteride 2 years ago

A user's 4-year journey of using Finasteride to improve their hairline, which they started noticing results from within the first month, and experienced significant shedding during the first year. They also tried Minoxidil but had heart palpitations so stopped taking it.

community My baldness started to destroy my life.

in Chat 6 upvotes 2 years ago

Hair loss caused insecurity and affected social life for a 21-year-old. Failed hair transplant led to mental breakdown and struggle with studies.

community Finasteride and manjuice: is yours watery?

in Finasteride/Dutasteride 13 upvotes 3 years ago

A user has been taking finasteride for 7 months and is experiencing watery semen as the only side effect. They are considering taking zinc supplements to improve this condition.

community 4.5 months of microneedling – progress

in Microneedling 300 upvotes 4 years ago

A user who has had positive results from using a regimen of microneedling, finasteride, minoxidil, peppermint oil, keto shampoo and DHT organic shampoo for hair growth. The conversation also addressed whether to use .5mg or 1mg of finasteride and the difference between dermapens and rollers.

community losing hair as a female 17-18 years old feels terrible

in Female 15 upvotes 4 years ago

A female, aged 17-18, is experiencing significant hair loss, feeling hopeless despite trying various treatments like leave-in conditioners, omega-3s, supplements, sulfate-free shampoo, and biotin. She is distressed as her hair continues to thin, affecting her body image and self-esteem.

community Balding at 19 should not be a thing

in Treatment 94 upvotes 1 week ago

A 19-year-old is experiencing hair loss and considering treatments like finasteride, oral minoxidil, and possibly dutasteride. Users suggest continuing with finasteride and minoxidil, with some recommending dutasteride for stronger results.

community 1 and half years using Finasteride, minoxidil and Dermarolling.

in Progress Pictures 1701 upvotes 1 month ago

The conversation discusses hair regrowth progress using finasteride, minoxidil, and dermarolling over 1.5 years. Users share experiences, regimens, and express skepticism and admiration for the results.

community Is finasteride shedding at month 8,9, 10... really a thing?

in Finasteride/Dutasteride 25 upvotes 1 month ago

Finasteride and minoxidil users discuss shedding around months 8-10, with mixed experiences on hair regrowth. Some consider switching to dutasteride if shedding persists.

community Dutasteride is for Young Hair Loss Suffers

in Finasteride/Dutasteride 104 upvotes 2 months ago

Dutasteride is discussed as a treatment for young hair loss sufferers, with mixed experiences regarding side effects and effectiveness. Some users report positive results with Dutasteride, while others prefer Finasteride or Minoxidil due to fewer side effects.

community Concerned about my child’s lack of density. Microneedling help?

in Satire 1010 upvotes 4 months ago

A user humorously discusses their 10-month-old's hair loss, suggesting treatments like microneedling, minoxidil, finasteride, and RU58841. Replies include various satirical and exaggerated suggestions, emphasizing the post's satirical nature.

community Does it look like improvement? 3 months on oral Minoxidil

in Is this regrowth? 797 upvotes 4 months ago

A user shared their 3-month experience with oral Minoxidil and nearly a year on finasteride, asking if a hair transplant might still be needed. Responses varied from congratulatory remarks on visible improvement to advice on sticking with treatments despite initial shedding.

community Some more realistic 15 months fin+min results. No loss, but also basically no growth. HT unfortunately seems like the only option left at this point :/

in Progress Pictures 116 upvotes 5 months ago

User shared 15-month results using finasteride and minoxidil, showing no loss but minimal growth, considering a hair transplant. Replies suggest starting treatment earlier, continuing current treatment, or getting a transplant.

community Herbacle hair growth serum with 0% min

in Product 19 upvotes 8 months ago

The conversation discusses the effectiveness of a new hair growth serum called HERBACLE, which claims to be the world's first, but lacks reviews and is doubted by users. One user notes that its ingredients are similar to those in The Ordinary's Multi-Peptide Serum for Hair Density.