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5 / 57 resultslearn Pyrilutamide
highly targeted anti-androgen that might have minimal systemic effects
learn KY19382
compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles
learn Alopecia Areata
autoimmune disorder causing patchy hair loss
learn PP405
mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
Research
5 / 1000+ results![Data from Synergistic Function of Smad4 and PTEN in Suppressing Forestomach Squamous Cell Carcinoma in the Mouse](/images/research/2d029b96-43f8-4de2-87b5-b423a6816688/small/38972.jpg)
research Data from Synergistic Function of Smad4 and PTEN in Suppressing Forestomach Squamous Cell Carcinoma in the Mouse
Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.
![Androgen Receptor Mutations and Polymorphisms in African American Prostate Cancer](/images/research/98b3f6aa-7ec2-43a9-acd7-62b31e7bba04/small/14421.jpg)
research Androgen Receptor Mutations and Polymorphisms in African American Prostate Cancer
African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.
![The Modulatable Stem Cell Niche: Tissue Interactions During Hair and Feather Follicle Regeneration](/images/research/a7c0abfa-a6ca-4c10-bcee-521fd7e0bd90/small/18486.jpg)
research The Modulatable Stem Cell Niche: Tissue Interactions During Hair and Feather Follicle Regeneration
The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
![Overexpression of Nanog in Amniotic Fluid-Derived Mesenchymal Stem Cells Accelerates Dermal Papilla Cell Activity and Promotes Hair Follicle Regeneration](/images/research/81c84dc2-7c7a-44b9-bbd8-096862775681/small/4576.jpg)
research Overexpression of Nanog in Amniotic Fluid-Derived Mesenchymal Stem Cells Accelerates Dermal Papilla Cell Activity and Promotes Hair Follicle Regeneration
Nanog gene boosts stem cells, helps hair growth, and may treat hair loss.
![The JAK/STAT Signaling Pathway: From Bench to Clinic](/images/research/2bd71fdd-78cc-478e-b70f-6d8d485cb0f1/small/17075.jpg)
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
Community Join
5 / 1000+ resultscommunity Does CosmeRNA target the root cause of MPB?
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CumsOnYourFeet69 has been discussing a new treatment called CosmeRNA which claims to target the root cause of male pattern baldness, and is considering using it in conjunction with Minoxidil instead of Finasteride due to possible side effects. Replies have highlighted that the efficacy of this treatment is still unknown, but it could be used as an effective maintenance option if successful.
community Long term finasteride users; Did you notice any improvement after 2 years?
Long term Finasteride users and whether or not they have noticed improvements after two years of use, with other treatments such as Minoxidil and dermarolling also discussed. Some replies suggest that improvement is possible even beyond the two year mark while others caution against believing studies backed by the Post-Finasteride Foundation.
community The Real Cause Of Androgenetic Alopecia
Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.
community HLT Megathread on HMI-115 (key takeaways in comments)
HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.
community I am waiting for cosmerna to come out but I don’t know how could I possibly apply 1ml on my whole scalp. I am mostly receding but i am also diffuse thinning everywhere and I think started losing my crown going into Norwood 4 basically
Hair loss treatments, specifically Minoxidil and the tap method; Finasteride was also discussed but not recommended due to its side effects. Price and other information were requested.