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an anticonvulsant repurposed for hair loss via histone inhibition
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Microscopic delivery system that sends growth-promoting signals to hair follicles
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research Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression (Catagen) by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla
All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
research Exhaustive analysis of scalp hair regression: subjective and objective perception from initial hair loss to severe miniaturisation and drug-induced regrowth
Hair loss reduces hair thickness and coverage, but drug treatments mainly revive dormant hairs rather than reverse thinning; patients often undervalue their hair loss severity.
research Effect of Behavioral Factors on Severity of Female Pattern Hair Loss: An Ordinal Logistic Regression Analysis
Avoid alcohol, ponytails, and oily scalp, and get good sleep to prevent severe hair loss.
research Mimicking Senescence Factors to Characterize the Mechanisms Responsible for Hair Regression and Hair Loss: An In Vitro Study
TGF-β1 and FGF-18 are key in hair loss, and Minoxidil helps hair growth.
research Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression
Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.
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5 / 1000+ resultscommunity Why does hairloss look great one day and regression the next?
Hair appearance fluctuates due to factors like styling, product buildup, and humidity, causing frustration for those with diffuse thinning. Treatments mentioned include minoxidil, finasteride, ketoconazole shampoo, and RU58841, with mixed results.
community 30M Seeing Gradual Recession, Family History of Hair Loss, Considering Finasteride
A 30-year-old with a family history of receding hairlines is considering starting finasteride due to gradual hairline recession. They are seeking advice on whether to begin treatment or if they are worrying unnecessarily.
community Me looking at my friends slight temple recession and calculating how long it'll take for him to bring it up to me, the Hairloss expert (I've been on finasteride for 6 months) so I can slap him with a 30 minute presentation about DHT miniaturization and 5-alpha reductase inhibitors
The post is a humorous take on the author's experience with hair loss and using finasteride for six months. The conversation includes discussions about hair loss, treatments like finasteride, and personal experiences with baldness.
community Dutasteride accelerated my hairloss, no shed tho
A user experienced worsening hair recession after adding 0.5 mg daily dutasteride to their regimen of topical minoxidil and finasteride, despite no initial shedding. They plan to continue monitoring the situation, as others suggest it may be too early to see results and recommend blood tests to check DHT levels.
community Tretinoin potentially can make hair loss worse ?
Tretinoin may worsen hair loss by inducing premature hair follicle regression. It can be used with minoxidil to increase absorption but should not be used alone.