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    GlossaryImmune Dysfunction

    immune system fails to protect the body properly

    Immune Dysfunction, also known as Immune System Disorder, refers to a condition where the immune system does not function properly. This can manifest as an overactive immune response, leading to autoimmune diseases where the body attacks its own tissues, or an underactive response, resulting in immunodeficiency where the body is unable to effectively fight off infections. Examples include conditions like rheumatoid arthritis (autoimmune) and HIV/AIDS (immunodeficiency).

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    5 / 5 results

      learn Baricitinib

      JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn Vitamin D

      vitamin you should probably be taking for general health might also help your hair a little

    Research

    5 / 1000+ results
      The Pathogenesis of Alopecia Areata

      research The Pathogenesis of Alopecia Areata

      89 citations, October 1996 in “Dermatologic Clinics”
      Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
      Evaluation of Some Biochemical Markers in Alopecia Areata

      research Evaluation of Some Biochemical Markers in Alopecia Areata

      January 2023 in “International journal of dermatology, venereology and leprosy sciences”
      People with alopecia areata have different blood markers that suggest inflammation and immune system issues compared to healthy individuals.
      Alopecia Areata: Pathogenesis And Treatment

      research Alopecia Areata: Pathogenesis And Treatment

      122 citations, November 1984 in “Journal of the American Academy of Dermatology”
      No single treatment is consistently effective for alopecia areata, and more research is needed.
      Gut Microbiome, Metabolome and Alopecia Areata

      research Gut Microbiome, Metabolome and Alopecia Areata

      2 citations, November 2023 in “Frontiers in microbiology”
      The health of the gut may be important in developing new ways to prevent, diagnose, and treat alopecia areata.

    Community Join

    5 / 264 results

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  738 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community If PP405 goes systemic this would be quite catastrophic

      in Research/Science  3 upvotes 3 months ago
      Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.

      community Medications that cause extra hair growth

      in Research/Science  123 upvotes 1 year ago
      The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 8 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.