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    Glossary Immune Cell

    Immune cells are specialized cells within the immune system that play a crucial role in defending the body against pathogens and foreign substances. In the context of hair loss, certain immune cells, such as T cells, can mistakenly target hair follicles, leading to conditions like alopecia areata, where hair is lost in patches due to an autoimmune response. Key distinguishing characteristics of immune cells include their ability to recognize and respond to antigens, as well as their diverse types, including lymphocytes, macrophages, and dendritic cells, each with specific functions in immune regulation and response. Understanding the role of immune cells in hair biology is essential for developing targeted therapies for autoimmune-related hair loss conditions.

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    Research 10 of 1000+

    1. Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack Journal of Investigative Dermatology · 2007 · 253 citations
    2. Gene Array Profiling and Immunomodulation Studies Define a Cell-Mediated Immune Response Underlying the Pathogenesis of Alopecia Areata in a Mouse Model and Humans Journal of Investigative Dermatology · 2002 · 114 citations
    3. Unraveling the ECM-Immune Cell Crosstalk in Skin Diseases Frontiers in Cell and Developmental Biology · 2019 · 97 citations
    4. Hair Follicle Mesenchyme-Associated PD-L1 Regulates T-Cell Activation Induced Apoptosis: A Potential Mechanism of Immune Privilege Journal of Investigative Dermatology · 2013 · 53 citations
    5. Immune cell regulation of the hair cycle Experimental Dermatology · 2020 · 27 citations
    6. RETRACTED: Causal role of immune cells in alopecia areata: A two‐sample Mendelian randomization study Skin Research and Technology · 2024 · 14 citations
    7. Eavesdropping on the conversation between immune cells and the skin epithelium International Immunology · 2019 · 10 citations
    8. Physiological Doses of Red Light Induce IL‐4 Release in Cocultures between Human Keratinocytes and Immune Cells Photochemistry and Photobiology · 2017 · 9 citations
    9. Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing Frontiers in Immunology · 2024 · 7 citations
    10. Skin-resident immune cells actively coordinate their distribution with epidermal cells during homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 7 citations
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    Learn 8 of 10

    1. Rapamycin Immune-suppressing drug, also called sirolimus
    2. Hair Multiplication extract, clone, and reinsert your own hair cells
    3. Alopecia Areata autoimmune disorder causing patchy hair loss
    4. Thymosin Beta 4
    5. Metformin Diabetes drug that lowers blood sugar
    6. Vitamin D Vitamin made in the skin from sunlight, also taken as a supplement
    7. Microneedling Technique that makes tiny punctures in the scalp with fine needles
    8. Neem Oil Oil from the neem tree, used in traditional remedies
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    Community 1 of 10

    1. Telogen Effluvium/Chronic TE and immune-related hair loss advice Reddit · 8 Aug 2018
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