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research The Effect of Topical Gel Secretome Hypoxic Mesenchymal Stem Cells (SH-MSCs) on IL-6 and TGF- β Gene Expression (Experimental Study in Male Wistar Alopecia-Like Rat Models Induced by Fluconazole)

December 2023 in “International journal of multidisciplinary research and analysis”

This study suggests that administering SH-MSCs gel might decrease IL-6 expression and increase TGF-β expression in alopecia-like rats, indicating potential for alopecia therapy.

research Interleukin 6 and STAT3 regulate p63 isoform expression in keratinocytes during regeneration

11 citations , November 2015 in “Experimental Dermatology”

This study reported that IL-6/STAT3 signaling influences p63 isoform expression in keratinocytes and is involved in wound-induced hair follicle neogenesis, highlighting the interplay between immune and developmental pathways.

research Ovarian leukocyte distribution and cytokine/chemokine mRNA expression in follicular fluid cells in women with polycystic ovary syndrome

69 citations , September 2006 in “Human Reproduction”

This study found that CD45RO+ cells, a subtype of T lymphocytes, were notably reduced in the ovarian follicles of women with PCOS, which may contribute to the condition's pathogenesis.

research ROBO4 deletion ameliorates PAF-mediated skin inflammation via regulating the mRNA translation efficiency of LPCAT1/LPCAT2 and the expression of PAF receptor

6 citations , January 2020 in “International journal of biological sciences”

In this study, deletion of ROBO4 in mice ameliorated hair loss caused by elevated PAF levels, suggesting potential interplay with VLDLR-related pathways.

research Increased expression of nerve growth factor and neurokinin-1 alarm the hair loss in female with trichodynia

March 2012 in “Journal of The American Academy of Dermatology”

Higher levels of certain nerve-related proteins are linked to hair loss in women with scalp pain.

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Community Join

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community Before & after for 3 months of minoxidil & 6 months of finasteride/minoxodil/tretinoin

658 upvotes 1 year ago

A 36-year-old experienced significant hair regrowth using minoxidil, finasteride, and tretinoin with minimal side effects. He plans to continue the treatment, hoping for more targeted solutions in the future.

community Turkey is constantly pouring money into fear mongering around finasteride in order to protect its hair transplant economy

119 upvotes 6 months ago

Finasteride and minoxidil are commonly recommended by hair transplant clinics, including those in Turkey, despite some negative perceptions and concerns about side effects. The conversation highlights differing opinions on the effectiveness and safety of these treatments, with some users expressing skepticism about side effects and others emphasizing the importance of these medications for successful hair transplants.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

14 upvotes 2 years ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community What's your option on complementary treatment

3 upvotes 2 years ago

The conversation discusses complementary treatments for hair loss while using finasteride and minoxidil, including scalp massagers, scrubs, coconut oil, and vitamin supplements. The user seeks opinions on these additional treatments.

community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

29 upvotes 2 months ago

Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Stem Cell Factor

learn Hair Transplant

What happens after a hair transplant? Expect mild swelling and redness, with new hair growth starting in 3 to 6 months.
Will people be able to tell I had a hair transplant? Most people won't notice a hair transplant if done by a skilled surgeon.
How should I sleep after a hair transplant? Sleep with your head elevated and on your back for the first 3-15 nights.
All 5 questions on Hair Transplant →

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Clinics

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Experts

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74
Hair Loss Specialist
Will Quaye
Crawley, England, United Kingdom

Will Quaye