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GlossaryInterleukin-7

protein crucial for T cell development and hair follicle maintenance

Interleukin-7 (IL-7) is a protein that plays a crucial role in the immune system by promoting the development and survival of T cells, which are essential for the body's defense against infections. It is also involved in the maintenance of hair follicles, and disruptions in IL-7 signaling can be linked to conditions like alopecia, where hair loss occurs due to immune system imbalances.

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research Hair Follicle-Derived IL-7 and IL-15 Mediate Skin-Resident Memory T Cell Homeostasis and Lymphoma

245 citations, October 2015 in “Nature medicine”

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

research Skin-Infiltrating CD4+ Lymphoma Cells Depend on Hair Follicle-Derived IL-7

September 2016 in “Journal of Dermatological Science”

Hair follicles produce IL-7, which is essential for certain skin lymphoma cells to survive.

research COVID-19: Understanding Inter-Individual Variability and Implications for Precision Medicine

58 citations, December 2020 in “Mayo Clinic Proceedings”

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

research Stimulation of Hair Follicle Stem Cell Proliferation Through an IL-1α Dependent Activation of γδ T-Cells

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

Certain immune cells, when activated by specific signals, can encourage hair growth.

research Cutting Edge: Memory Regulatory T Cells Require IL-7 and Not IL-2 for Their Maintenance in Peripheral Tissues

140 citations, March 2013 in “The journal of immunology/The Journal of immunology”

Memory regulatory T cells need IL-7, not IL-2, to stay in peripheral tissues.

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community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 6 months ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.