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Risk Factors for Prostate Cancer: A Case-Control Study Investigating Key Exposures and Gene Interactions

research Risk factors for prostate cancer: a case-control study investigating selected key exposures and their interactions with predisposition genes

December 2010 in “Jurnal Natural (Faculty of Mathematics and Natural Science, Syiah Kuala University)”

This thesis explores both environmental and genetic factors in prostate cancer, focusing on surrogate hormone markers, medical radiation, family history, and genetic polymorphisms related to DNA repair and hormone marker genes, but reports no new clinical findings.

research Identifying genes associated with the development of human polycystic ovary syndrome

31 citations , January 2020 in “Saudi Journal of Biological Sciences”

This review examines how polymorphisms in androgen-related genes may influence genetic predisposition to PCOS but reports no consistent genetic marker.

research Gene expression profile of human follicle dermal papilla cells in response to Camellia japonica phytoplacenta extract

3 citations , January 2021 in “FEBS open bio”

This study found that a solution containing 0.5% Camellia japonica placenta extract increased scalp moisture and reduced sebum content, dead keratin, and erythema in adult females, suggesting potential as a scalp treatment.

research Ganoderma lucidum extract attenuates corticotropin-releasing hormone induced cellular senescence in human hair follicle cells

April 2024 in “iScience”

Ganoderma lucidum extract may help treat stress-related hair loss.

research Factors associated with early-onset androgenetic alopecia: A scoping review

March 2024 in “PLOS ONE”

This review explores the risk factors, associated comorbidities, and psychological impacts of early-onset androgenetic alopecia, highlighting its complexity and potential implications for treatment response and overall health.

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Community Join

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community Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits

140 upvotes 11 months ago

Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.

community Finasteride stopped working. Losing ground on Dutasteride.

in Finasteride/Dutasteride 17 upvotes 4 months ago

The user started with Finasteride at 19, added Dutasteride and Minoxidil at 26, but continues to experience hair loss. Suggestions include checking health markers, considering genetics, and possibly increasing Minoxidil dosage.

community Switched from finasteride to dutasteride - 2 month update

in Finasteride/Dutasteride 6 upvotes 2 years ago

The user switched from finasteride to dutasteride for hair loss treatment, but experienced increased libido, itchy scalp, and accelerated hair loss. Another user suggested that genetic variations might cause dutasteride to be less effective and recommended checking for specific genetic markers.

community Hormone tests to decide on oral fin

4 upvotes 1 year ago

The conversation discusses starting low-dose oral finasteride for hair loss, considering hormone levels and potential side effects like gynecomastia. Suggestions include using DIM for estradiol, vitamin B6 for prolactin, and lifestyle changes to optimize hormone profiles before starting treatment.

community Check your hormones before dropping Finasteride if you are getting symptoms

59 upvotes 1 month ago

High body fat can increase estrogen levels, leading to side effects when using finasteride. Reducing body fat and checking hormone levels can help manage these side effects.

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Learn

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learn sh-Polypeptide-7

learn Dutasteride

Heavy duty finasteride that comes with higher risks

learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Follistatin

Is follistatin safe for use in women or transgender individuals undergoing hormone therapy? No study has tested follistatin in women or transgender people on hormone therapy, and it has no approved human use or established dose; the one relevant signal, from a 2023 randomized study in adolescents with PCOS, links higher follistatin to less favourable metabolic markers, so the published evidence does not support using it in this group.

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