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research Glycolipid and Hormonal Profiles in Young Men with Early-Onset Androgenetic Alopecia: A meta-analysis

15 citations , August 2017 in “Scientific Reports”

This study found that young men with early-onset androgenetic alopecia have a worse glycolipid profile and hormone pattern similar to women's PCOS, suggesting a possible male PCOS-equivalent syndrome.

research The Safety of Local Hormonal Treatment for Vulvovaginal Atrophy in Women With Estrogen Receptor-positive Breast Cancer Who Are on Adjuvant Aromatase Inhibitor Therapy: Meta-analysis

18 citations , August 2019 in “Clinical breast cancer”

This meta-analysis found that in postmenopausal women with a history of breast cancer, 8 weeks of vaginal estrogen therapy while on aromatase inhibitors did not result in systemic absorption of sex hormones, suggesting potential safety for treating vulvovaginal atrophy in this context.

research Venous and pulmonary thromboembolism and combined hormonal contraceptives. Systematic review and meta-analysis

63 citations , January 2012 in “The European Journal of Contraception & Reproductive Health Care”

This study concluded that combined hormonal contraceptives containing desogestrel, drospirenone, or cyproterone acetate were associated with a higher risk of venous thromboembolism compared to those containing levonorgestrel.

research LB1047 Comparative analysis of cutaneous hormonal profiles in pre-menopausal and post-menopausal women

July 2024 in “Journal of Investigative Dermatology”

Skin hormone levels change significantly after menopause.

research Prevalence of hormonal and endocrine dysfunction in patients with lichen planopilaris (LPP): A retrospective data analysis of 168 patients

44 citations , February 2017 in “Journal of the American Academy of Dermatology”

This study found that postmenopausal women with lichen planopilaris showed a high prevalence of androgen excess, while women with frontal fibrosing alopecia were often associated with androgen deficiency.

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community Possible transgenerational effects of finasteride use on male offspring? (STUDY)

in Research/Science 27 upvotes 4 months ago

Finasteride may affect male offspring's fertility and hormonal balance, with debates on whether to discontinue use before conception. Some users report no issues, while others highlight the high doses used in rat studies.

community Minoxidil is a 5ar inhibitor according to research

150 upvotes 11 months ago

Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

community Latest study on RU58841 done 19. August 2026.

25 upvotes 1 month ago

RU58841 can be absorbed systemically after topical application, but the study did not find immediate hormonal disruption. The study highlights the need for more research on long-term safety and effects of RU58841, as well as the importance of quality control in products from the grey market.

community How many are hyper responders to Finasteride?

6 upvotes 4 months ago

The user experienced severe side effects from finasteride, including hormonal imbalances and cognitive issues, leading to a recommendation to stop its use. They plan to follow up with tests to rule out a pituitary tumor and are considering topical treatments as alternatives.

community Does finasteride decrease free testosterone?

in Research/Science 186 upvotes 1 year ago

Finasteride may decrease free testosterone by increasing SHBG, potentially causing side effects like reduced libido and hormonal changes. Some find it effective for hair loss, while others experience negative effects.

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Learn

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learn Overview

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Thymosin Beta 4

learn Stem Cell Factor

learn Lavender

Is lavender effective for hormonal hair loss or just stress? Lavender may help with stress-related hair loss but has limited evidence for hormonal hair loss.

learn procapil

Want to stop hormonal hair loss without touching your hormone levels? Procapil could block the enzyme doing the damage. Procapil's supplier describes it as inhibiting 5-alpha reductase at the scalp without changing hormone levels, but the published support is cell and animal work plus one small human study of a caffeine-plus-Procapil formula. It is a cosmetic ingredient, not an approved hair-loss treatment, and no trial has compared it with finasteride or minoxidil.

learn Baicapil

Losing hair from hormonal imbalance? Baicapil might block DHT without messing with your hormones. No published study shows that Baicapil blocks DHT — the only data on the ingredient itself is the manufacturer's own unpublished dossier, and the baicalin research behind the claim is cancer cell-line work in which the effect was explicitly independent of the androgen receptor.

learn Adenosine

Adenosine : Can it help if my hair loss is due to a hormonal imbalance like PCOS or DHT? Adenosine may help improve hair growth affected by hormonal imbalances like PCOS or DHT.

learn Bicalutamide

Why are some women using bicalutamide to fight hormonal hair loss? Bicalutamide blocks androgens, helping women combat hormonal hair loss effectively.

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