26 citations
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June 2001 in “PTR. Phytotherapy research/Phytotherapy research” This study reported that a 1% procyanidin B-2 tonic increased hair diameter and density in men with male pattern baldness, suggesting it may be a potential treatment option.
10 citations
,
January 2004 in “PubMed” This study observed that gamma-ray induced apoptosis in ICR mouse hair follicles could be reduced by pretreatments with diethyldithiocarbamate or green tea, suggesting these agents as potential radioprotectors.
32 citations
,
December 2000 in “Phytomedicine” In this study, 1% procyanidin B-2 tonic significantly increased the number of total and terminal hairs on the scalp of male participants compared to a placebo after 6 months of use.
28 citations
,
December 2005 in “Journal of cosmetic dermatology” This study found that 0.7% apple procyanidin oligomers applied externally for six months significantly increased hair growth in men with male pattern baldness compared to placebo, with no observed adverse effects.
30 citations
,
May 1999 in “Food and chemical toxicology” This study suggests that topical procyanidin B-2 is safe for use as a hair growth agent, as it showed no mutagenic effects or significant irritation in a series of toxicological tests.