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research Severe diffuse non-scarring hair loss in systemic lupus erythematosus - clinical and histopathological analysis of four cases

15 citations , December 2011 in “Journal of the European Academy of Dermatology and Venereology”

In this study, severe diffuse hair loss in patients with systemic lupus erythematosus was associated with distinct clinical, dermoscopic, and histopathological features, which improved alongside treatment of the underlying condition.

research Hair melanocytes as neuro-endocrine sensors—Pigments for our imagination

43 citations , October 2005 in “Molecular and cellular endocrinology”

This review discusses how the CRH/POMC systems may regulate human hair follicle pigmentation and highlights the concept of "self-similarity" in melanocortin systems at both local and systemic levels, without presenting new experimental results.

research Topical RT1640 treatment effectively reverses gray hair and stem cell loss in a mouse model of radiation‐induced canities

7 citations , July 2020 in “Pigment cell & melanoma research”

In this study, RT1640 was found to promote hair pigment system regeneration and expand melanocyte stem cell pools in a mouse model, suggesting potential applications for aging-related hair disorders.

research Reconstructing hair follicle pigmentary unit using organoids and bioprinting

August 2026 in “International Journal of Bioprinting”

This review highlights the complexities of hair graying and the limitations of current models to fully replicate hair follicle pigmentary unit function, suggesting that technologies like organoids and bioprinting show promise but require further development for effective hair repigmentation interventions.

research Development And Evaluation of Natural Hair Dye Formulations

May 2026 in “Zenodo (CERN European Organization for Nuclear Research)”

This review summarizes current research on natural hair dyes, reporting that plant-based formulations can safely provide viable colors on gray hair with minimal irritation compared to synthetic options but face challenges in color range and consistency.

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Learn

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learn Scalp Micropigmentation

Does scalp micropigmentation look natural? Scalp micropigmentation can look natural if performed by a skilled practitioner.
What is Scalp Micropigmentation and how does it help people with visible hair loss? Scalp Micropigmentation creates the illusion of hair follicles on the scalp for visible hair loss.
Is scalp micropigmentation safe? Providers describe scalp micropigmentation as low-risk when a trained practitioner uses sterile single-use equipment, but that is a provider claim rather than a regulatory finding: pigment allergy, infection and colour change are documented risks of cosmetic tattooing.
All 5 questions on Scalp Micropigmentation →

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

learn Stem Cell Factor

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Community Join

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community Making your own RT1640 in China

4 years ago

RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

community Dr. Tsuji Hair Cloning Exclusive Interview

17 upvotes 1 year ago

Hair cloning for hair loss is unlikely to be available or affordable in the next 10 years. Current treatments like Minoxidil, finasteride, and RU58841 are still the main options, with skepticism about new advancements.

community Dht kills hair, but no one says why?

in Finasteride/Dutasteride 40 upvotes 1 year ago

DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

community Why don’t more people use hair fibers?

in Product 527 upvotes 11 months ago

Hair fibers can effectively cover thinning hair when used with minoxidil and hairspray but require daily application and can be inconvenient in certain conditions. Some users prefer treatments like finasteride, dutasteride, microneedling, or wigs due to the maintenance and limitations of hair fibers.

community South Korea is debating whether hair loss should be covered by public healthcare. That alone says a lot about how we still misunderstand hair loss.

67 upvotes 8 months ago

South Korea is debating whether hair loss treatments should be covered by public healthcare, highlighting the issue's impact on mental health and social functioning. The discussion centers on whether hair loss should be classified as a medical condition rather than a cosmetic issue, considering its psychological effects and the biological processes involved.

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Clinics

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Experts

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas