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GlossaryHaCaT cells

immortalized human skin cells used for research

HaCaT cells are a type of immortalized human keratinocyte cell line, which means they are skin cells that have been modified to divide indefinitely in laboratory conditions. These cells are commonly used in scientific research to study skin biology, wound healing, and diseases like psoriasis and skin cancer, because they closely mimic the behavior of normal human skin cells.

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research Network Pharmacological Study of Ethyl Acetate Fraction of Ophioglossum Vulgatum Linn. in Alopecia Treatment

December 2022 in “Research Square (Research Square)”

The ethyl acetate fraction of Ophioglossum vulgatum Linn. may promote hair growth and could be a new herbal treatment for hair loss.

research Gene Expression Profiling of Human Keratinocytes Exposed to the Hair-Dyeing Agent, m-Aminophenol

March 2013 in “Molecular & Cellular Toxicology/Molecular & cellular toxicology”

m-Aminophenol in hair dye can cause skin cell toxicity and stress responses.

research HaCaT Cell Proliferation Influenced by Melatonin

28 citations , January 2003 in “Skin pharmacology and physiology”

Melatonin affects skin cell growth differently based on how much and how long it's used.

research Cell Density-Dependent Upregulation of PDCD4 in Keratinocytes and Its Implications for Epidermal Homeostasis and Repair

10 citations , December 2015 in “International Journal of Molecular Sciences”

PDCD4 is important for controlling skin cell growth and healing.

research Epithelial Cell Migration on Laminins

January 2004 in “Kölner Universitäts PublikationsServer (Universität zu Köln)”

Collagen XVII and CD151 affect cell movement, with CD151 inhibiting migration when bound to integrins.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Anti-oxidants that reverse hairloss?

in Research/Science 88 upvotes 5 years ago

Resveratrol and fisetin, found in red wine and strawberries, may promote hair growth by affecting hair follicle cells. Users discuss various treatments, including natural remedies like saw palmetto and topical applications, with mixed opinions on their effectiveness compared to pharmaceuticals like finasteride.

community Minoxidil is a 5ar inhibitor according to research

in Research/Science 147 upvotes 5 months ago

Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

community Minoxidil is NOT an Anti-androgen. No.

in Research/Science 43 upvotes 4 months ago

Minoxidil is not an anti-androgen; it is a growth stimulator and does not lower DHT like finasteride or dutasteride. Minoxidil can cause side effects like facial swelling and anxiety due to its vasodilator properties.

community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 1 year ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

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