research Metabolism and skin diseases
Skin health and diseases are closely linked to metabolic processes.
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5 / 1000+ resultsresearch Signal transducer and activator of transcription 5B deficiency due to a novel missense mutation in the coiled-coil domain
In this study, a novel homozygous mutation in the STAT5B gene was identified in a 17-year-old boy with growth hormone-refractory growth failure, severe eczema, and autoimmune disease, suggesting a similarity to known STAT5B deficiency phenotypes.
research Testosterone Hormone ; Clinical Indications, Dysregulation and Therapeutic methods
This review summarizes the latest evidence on testosterone, detailing its clinical indications, diagnostic tests, and impacts on various male organs, while also noting its association with aging, metabolic disorders, and increased mortality risk due to androgen deficiency.
research Hairless is a nuclear receptor corepressor essential for skin function
This study identified the Hairless (Hr) gene-encoded protein as a corepressor that plays a crucial role in maintaining skin and hair by regulating epithelial stem cell differentiation and gene expression via chromatin remodeling, which may impact both development and disease.
research Scoring systems for pemphigus
This review by Boucher et al. highlights the Pemphigus Disease Area Index and Autoimmune Bullous Skin Disorder Intensity Score as the most valid and reliable tools for assessing pemphigus severity but notes that simplified scores like IGAs require further validation.
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5 / 1000+ resultscommunity Hair loss research focused on chemistry for decades because we misunderstood the mechanics of growth.
Hair growth relies on mechanical forces, not just chemicals, with tissue acting like a motor. Minoxidil and finasteride help, but maintaining tissue elasticity and addressing mechanical issues are essential.
community I just don’t understand this
Finasteride is discussed for hair loss treatment, with opinions divided on its safety and effectiveness. Some consider natural remedies, but these may also affect hormones.
community How finasteride lowers brain's happiness steroid allopregnanolone and causes depression: systemic dihydroprogesterone crosses blood brain barrier, you don't even need finasteride and brain 5ar for that
Finasteride may lower allopregnanolone levels, potentially affecting mood, but many users report improved mental health due to reduced hair loss. Experiences with finasteride and dutasteride vary, with some experiencing side effects and others finding them beneficial for hair retention and overall happiness.
community Positive Hair Result in Patient using Tirzepatide
A 57-year-old man with male pattern hair loss and insulin resistance experienced hair regrowth and weight loss after using tirzepatide, without other hair treatments. Dysregulated glucose metabolism is linked to hair loss, with tirzepatide potentially improving hair density by normalizing insulin resistance.
community Female diffuse hair loss on spiro with irregular periods (photos) + genetic hair loss
A 34-year-old woman is experiencing diffuse hair loss and irregular periods, possibly due to long-term spironolactone use. She is considering minoxidil and finasteride for treatment and seeking medical advice for androgenic alopecia and hormonal imbalances.
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5 / 800 results- How does Vascular Endothelial Growth Factor (VEGF) differ from DHT-blocking treatments for androgenic alopecia? VEGF promotes blood vessel growth, while DHT-blocking treatments reduce hormone effects on hair follicles.
- What does Fluridil do on the scalp, and how does it block the DHT hormone? Fluridil is a topical anti-androgen sold in some European countries. One small 2002 trial led by its developer reported more hairs in the growth phase; it is not FDA-approved and the evidence is limited.
- Are there any safety concerns or allergic reactions associated with sh-Polypeptide-7 in topical hair products? sh-Polypeptide-7 is recombinant human growth hormone, and no published human study has tested its safety on the scalp, so its safety is not established. Dermatologists commonly advise patch testing a new scalp product, and people who are pregnant, breastfeeding, or have diabetes, a history of cancer or an endocrine condition should ask a doctor first.
- What is sh-Polypeptide-7 and why is it used in some advanced hair serums and treatments? sh-Polypeptide-7 is the cosmetic-ingredient name for recombinant human growth hormone. It is marketed in hair and scalp products, but no published human trial shows that it helps hair growth, and its safety on the scalp has not been studied.
- Is sh-Polypeptide-7 considered a natural or synthetic ingredient, and how is it typically applied? sh-Polypeptide-7 is a synthetic (lab-made) form of human growth hormone, used in some topical skin and hair-care products. There is no published human trial showing that it benefits hair, and its safety on the scalp has not been studied.
learn Vascular Endothelial Growth Factor
learn Exosomes
learn sh-Polypeptide-7
learn Estradiol
Estrogen hormone, prescribed in tablet, patch and gel forms
learn Melatonin
Hormone that regulates sleep, sold as a supplement
Clinics
6 / 71 results- Hair SystemsBalance Hormone CenterChandler · US
- Hair SystemsCarolina Hormone and HealthMt Pleasant · US
- Hair Loss TreatmentsThe Hormone ConnectionWalker, LA · US
- Hair Loss TreatmentsAbsolute HormoneLas Vegas, NV · US
Hair TransplantBalance Hormone CenterChandler, AZ · US
Hair TransplantCarolina Hormone and HealthMount Pleasant, SC · US
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