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5 / 5 resultslearn Aminobutyric Acid
learn Valproic acid
 an anticonvulsant repurposed for hair loss via histone inhibition  
 learn Osteopontin
 signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss  
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Research
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  research Proliferation, But Not Apoptosis, Is Associated With Distinct Beta-Catenin Expression Patterns in Non-Small-Cell Lung Carcinomas
 Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.  
  
  research Role of the Wnt Signaling Pathway in Keratoacanthoma
 The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.  
  
  research Stretching the Limits: From Homeostasis to Stem Cell Plasticity in Wound Healing and Cancer
 Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.  
  
  research Histogenesis of Keratoacanthoma: Histochemical and Immunohistochemical Study
 Keratoacanthoma comes from hair follicle cells.  
  
  research Paternal Finasteride Treatment Can Influence the Testicular Transcriptome Profile of Male Offspring—Preliminary Study
 Father's finasteride use may affect son's fertility and testicular function.  
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5 / 26 resultscommunity DHT Oily Scalp Dangers: Theory of an Oily Scalp and PPAR-GAMMA Dysregulation
 Excessive scalp sebum, worsened by DHT, can lead to inflammation and hair loss, with clascoterone mentioned as a treatment. Diet changes seem ineffective for scalp sebum, and treatments like minoxidil and finasteride are suggested.  
 community Is tazarotene potentially better than tretinoin in combination with topical minoxidil?
 Tazarotene may be more effective than tretinoin when combined with topical minoxidil for hair loss due to its selective binding to RAR-beta and gamma, though it can cause irritation. Tazarotene's potency can lead to indirect inflammatory reactions despite potentially causing less irritation than tretinoin.  
  
  community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied
 Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.  
 community Has anyone here tried taking GLA supplements?
 GLA may help with hair loss due to its anti-inflammatory properties and 5ar enzyme inhibition. It's considered potentially more important than biotin, especially for those already using finasteride and dutasteride.  
 community You will lose hair if your prostaglandins aren't in balance
 Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.