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community Fallopia multiflora (Fo-Ti) for Hair Regrowth?

3 upvotes 12 years ago

Fo-Ti is discussed as a potential treatment for hair loss, but its effectiveness is questioned. Users express skepticism and caution about its use.

community For anybody else feeling like a dough boy on oral min

7 upvotes 6 days ago

Users discuss managing side effects of oral Minoxidil, such as facial puffiness, with suggestions like using dandelion root as a diuretic and adjusting dosages. Some users consider topical alternatives and dietary changes to reduce fluid retention.

community Four months on dutasteride/minoxidil oral

68 upvotes 3 weeks ago

A 44-year-old has been using a combination of oral dutasteride (0.5mg), minoxidil (2.5mg), and biotin (10mg) daily for four months, noticing hair regrowth with some concern about side effects like numbness. Another user increased their dutasteride dose from 0.5mg to 1mg, reporting significant hair growth without side effects.

community For older guys: I'm 38 and been on FIN for 10-11 years... should I make the switch to DUT?

6 upvotes 3 weeks ago

A 38-year-old considering switching from finasteride and minoxidil to dutasteride for hair maintenance, noting past success with finasteride but recent hair shedding. Users shared experiences, with some recommending dutasteride for better regrowth, while others noted potential shedding during the transition.

community Why is foam minoxidil so much more expensive than liquid min?

in Minoxidil 6 upvotes 4 weeks ago

Foam minoxidil is more expensive because it dries faster and doesn't leave residue, unlike liquid minoxidil. Some users suggest using oral minoxidil for convenience and cost-effectiveness.

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Research

5 / 1000+ results

research Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation

990 citations , October 1999 in “Development”

This study found that LEF1/TCF3 is necessary but not sufficient for TOPGAL activation in hair follicle development, indicating complex regulation in the skin.

research Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

475 citations , October 2006 in “Proceedings of the National Academy of Sciences”

This study suggests that folliculin, mutated in Birt–Hogg–Dubé syndrome, and its partner FNIP1 may play a role in energy and nutrient sensing through the AMPK and mTOR pathways.

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Learn

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learn Fo-ti

learn Follistatin

Protein that blocks activin, a growth-regulating signal

learn Follicusan

learn Folic acid

Can folic acid help reduce hair loss in men and women, and how should it be taken? Correcting a confirmed folate deficiency is reasonable, but no published trial shows folic acid supplementation reduces hair loss on its own; the evidence is a few small observational studies and reviews that call for proper trials.
Is there a difference between taking folic acid supplements and using folic acid in topical hair products? Oral folic acid uses the body's normal absorption route and can correct a measured deficiency, but no published trial shows it treats hair loss; topical folic acid has no human evidence for hair growth, and no published human data show how much of it a plain shampoo or serum gets through the skin barrier.
How does folic acid support hair follicle health and growth at a cellular level? Folate is required for the DNA synthesis that fast-dividing hair matrix cells depend on, and severe deficiency causes anemia—but no published trial has given folic acid to people with hair loss and measured the result, so a growth effect is a mechanism, not a finding.
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