Search

for
Search:

Research

5 / 1000+ results

research Selected variants of the steroid-5-alpha-reductase isoforms SRD5A1 and SRD5A2 and the sex steroid hormone receptors ESR1, ESR2 and PGR: No association with female pattern hair loss identified

18 citations , February 2012 in “Experimental Dermatology”

This study found no significant association between selected gene variants and female pattern hair loss, suggesting these genes might not be involved in its development.

research Thyrotropin-releasing hormone and oestrogen differentially regulate prolactin and prolactin receptor expression in female human skin and hair follicles in vitro

37 citations , March 2010 in “British Journal of Dermatology”

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

research Luteinizing Hormone and Human Chorionic Gonadotropin Decrease Type 2 5α-Reductase and Androgen Receptor Protein Levels in Women’s Skin

13 citations , May 1998 in “The Journal of Clinical Endocrinology & Metabolism”

This study found that hCG decreased 5α-reductase and androgen receptor levels in skin samples from women in vitro, suggesting that human skin responds to LH/hCG treatment.

research A New Role of Non-Sex Hormone in the Pathogenesis of Female Pattern Hair Loss

August 2025 in “Journal of Investigative Dermatology”

Elevated luteinizing hormone contributes to female-pattern hair loss, and blocking certain channels may help prevent it.

research Human Female Hair Follicles Are a Direct, Nonclassical Target for Thyroid-Stimulating Hormone

90 citations , December 2008 in “Journal of Investigative Dermatology”

Thyroid-stimulating hormone affects hair follicles but doesn't change hair growth or color.

View more "female hormone receptor" in research →

Community Join

5 / 1000+ results

community SOS – The cure for women = PREGNANCY

2 upvotes 7 months ago

Pregnancy can temporarily reverse hair loss in women, but attempts to mimic pregnancy hormones with treatments like contraceptive pills, spironolactone, estradiol, progesterone, finasteride, and minoxidil have been ineffective. The discussion highlights the need for research into the hormonal mechanisms of pregnancy that affect hair regrowth.

community Clascoterone might be the Finasteride for female pattern hair loss.

9 upvotes 2 months ago

Clascoterone, a topical anti-androgen, shows promise for treating female pattern hair loss without systemic side effects, offering a potential alternative to minoxidil. It could also benefit men who experience side effects from finasteride.

community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

55 upvotes 2 years ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

community Female 37/F - On Meds, but no progress. Add PRP?

4 upvotes 3 years ago

A 37-year-old woman with androgenetic alopecia is using spironolactone, oral and topical minoxidil, and considering PRP therapy due to lack of progress. She is unable to obtain finasteride, dutasteride, or bicalutamide and is exploring other options like Clascoterone and RU58841.

community Female diffuse hair loss on spiro with irregular periods (photos) + genetic hair loss

in Female 16 upvotes 2 years ago

A 34-year-old woman is experiencing diffuse hair loss and irregular periods, possibly due to long-term spironolactone use. She is considering minoxidil and finasteride for treatment and seeking medical advice for androgenic alopecia and hormonal imbalances.

View more "female hormone receptor" in community →

Learn

8 / 800 results

learn Estradiol

Estrogen hormone, prescribed in tablet, patch and gel forms

Why is Estradiol used to treat hair loss in women and transgender people undergoing hormone therapy? Estradiol is used within supervised hormone therapy and may slow hormone-related hair loss in some women and trans women, but the evidence is limited and it carries serious whole-body risks.

learn Melatonin

Hormone that regulates sleep, sold as a supplement

learn Bicalutamide

Nonsteroidal anti-androgen, originally a prostate cancer drug

learn Neem Oil

Oil from the neem tree, used in traditional remedies

learn Follistatin

Is follistatin safe for use in women or transgender individuals undergoing hormone therapy? No study has tested follistatin in women or transgender people on hormone therapy, and it has no approved human use or established dose; a 2023 study in 72 adolescents with PCOS found that the body's own follistatin rose on estrogen-containing contraceptives alongside less favourable metabolic markers, a correlation that does not show follistatin caused them. The published evidence does not support using it in this group.

learn Pumpkin seed oil

Does pumpkin seed oil block DHT, the hormone linked to male and female pattern baldness? Pumpkin seed oil has not been shown to lower DHT in people. One small, supplier-funded trial of a branded supplement reported more hair after 24 weeks but did not measure DHT (Cho et al. 2014).

learn Hair Transplant

What causes male pattern baldness? Male pattern baldness is caused by genetic sensitivity to the hormone DHT.

learn Alfatradiol

Alfatradiol: What does a form of estrogen have to do with hair loss in men? Alfatradiol (17α-estradiol) is a topical hormone sold without prescription in German pharmacies, licensed there for mild androgenetic alopecia, and not FDA-approved. The controlled trial evidence is in women, where hair density and thickness stayed nearly unchanged over 6 months while minoxidil improved them (the trial had no placebo group); no comparable placebo-controlled trial in men appears to have been published.

View more "female hormone receptor" in learn →

Clinics

6 / 12 results

All 12 clinic results →

Experts

— no results

Try a deeper search in experts →