222 citations
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January 2003 in “Critical Reviews in Therapeutic Drug Carrier Systems”
This review discusses the capabilities of ethosomes as drug delivery carriers and reports improved outcomes in a clinical study with an ethosomal acyclovir formulation.
189 citations
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March 2018 in “Human Reproduction Update”
This study reported that women with polycystic ovary syndrome had a higher prevalence of impaired glucose tolerance and type 2 diabetes, with variations influenced by ethnicity and obesity.
182 citations
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January 2000 in “Drug Development Research”
This study found that ethosomal carriers enhanced dermal and transdermal drug delivery more effectively than classic liposomes, improving delivery to deep skin layers and showing potential for treating conditions like herpes labialis and diabetes.
ET-02 is seen as promising for addressing hair loss and graying, but PP405 is more advanced in development and has better publicity. Some users plan to use both treatments alongside minoxidil and dutasteride.
ET-02, a PAI-1 inhibitor, is not proven to be more effective than Minoxidil for hair loss. Other treatments like finasteride, dutasteride, PP405, and AMP-303 are also discussed, focusing on cellular senescence and oxidative stress.
ET-02 showed significant hair growth in five weeks, outperforming minoxidil, with a non-hormonal mechanism that avoids side effects of treatments like finasteride. A phase 2 trial is planned to further assess ET-02's efficacy and safety.
ET-02 (RS 5441) shows promising results for hair growth, performing better in humans than in mice. There is debate over the effectiveness compared to minoxidil, with some users wanting more detailed data.
Eirion Therapeutics is recruiting for phase 1 of ET-02 in Texas, which showed promising hair growth results in non-clinical studies. ET-02 demonstrated significantly more hair growth compared to Minoxidil.
Can I use hair loss treatments (finasteride, minoxidil) after scalp micropigmentation?About half of clinics say finasteride can continue through scalp micropigmentation, and about half ask clients to pause topical minoxidil during the sessions and for roughly 30 days afterwards. That pause is clinic aftercare convention, not a label instruction - ask your prescriber first, because stopping minoxidil usually causes shedding.