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GlossaryEtretinate

synthetic retinoid used to treat severe skin conditions

Etretinate is a medication that was used to treat severe psoriasis, a skin condition that causes red, scaly patches. It is a synthetic retinoid, which means it is related to vitamin A and works by slowing down the growth of skin cells. However, due to its long half-life and potential for serious side effects, it has been largely replaced by acitretin, a related drug with a shorter half-life.

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research Actions of Isotretinoin and Etretinate on the Pilosebaceous Unit

46 citations, April 1982 in “Journal of the American Academy of Dermatology”

Isotretinoin shrinks sebaceous glands without affecting hair or skin color, unlike etretinate.

Treatment of Localized Scleroderma and Lichen Sclerosus with Etretinate

research Treatment of Localized Scleroderma and Lichen Sclerosus with Etretinate

40 citations, March 1984 in “Acta dermato-venereologica”

Etretinate has only moderate effects on localized scleroderma and lichen sclerosus.

A Study of Etretinate-Induced Alopecia

research A Study of Etretinate-Induced Alopecia

34 citations, June 1990 in “British Journal of Dermatology”

Etretinate treatment changed hair growth patterns in many patients.

research Oral Treatment of Keratinizing Disorders of Skin and Mucous Membranes With Etretinate

31 citations, February 1982 in “Archives of dermatology”

Etretinate was effective for certain skin conditions, but caused side effects like chapped lips, dry mucous membranes, and hair loss.

Novel Cycle Changes in Scalp Hair Are Caused by Etretinate Therapy

research Novel Cycle Changes in Scalp Hair Are Caused by Etretinate Therapy

24 citations, March 1995 in “British Journal of Dermatology”

Etretinate therapy can cause hair loss by disrupting the hair growth cycle.

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