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GlossaryEtretinate

synthetic retinoid used to treat severe skin conditions

Etretinate is a medication that was used to treat severe psoriasis, a skin condition that causes red, scaly patches. It is a synthetic retinoid, which means it is related to vitamin A and works by slowing down the growth of skin cells. However, due to its long half-life and potential for serious side effects, it has been largely replaced by acitretin, a related drug with a shorter half-life.

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research Manifest Hair Repigmentation Associated with Etretinate Therapy

9 citations , July 2016 in “The Journal of Dermatology”

An 82-year-old man's white hair regained color after taking etretinate for psoriasis.

research Novel Drugs Targeting Retinoic Acid Receptors

January 2005

Newer retinoid drugs are effective for skin conditions but have significant side effects.

research Panel Discussion: The Efficacy of Retinoids in the Treatment of Psoriasis

April 1982 in “Journal of The American Academy of Dermatology”

Retinoids help treat psoriasis effectively, but they can cause side effects and need more research on safe use with other treatments.

research Oral Treatment of Keratinizing Disorders of Skin and Mucous Membranes With Etretinate

31 citations , February 1982 in “Archives of dermatology”

Etretinate was effective for certain skin conditions, but caused side effects like chapped lips, dry mucous membranes, and hair loss.

research Actions of Isotretinoin and Etretinate on the Pilosebaceous Unit

46 citations , April 1982 in “Journal of the American Academy of Dermatology”

Isotretinoin shrinks sebaceous glands without affecting hair or skin color, unlike etretinate.

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