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GlossaryPhosphorylation of ERK (ERK activation)

process activating ERK protein by adding phosphate groups

Phosphorylation of ERK, also known as ERK activation, refers to the process where the extracellular signal-regulated kinase (ERK) protein is activated by the addition of phosphate groups. This activation is a crucial step in the MAPK/ERK signaling pathway, which transmits signals from the cell surface to the DNA in the cell nucleus, influencing cell functions such as division, differentiation, and survival. This process is significant in various biological contexts, including hair growth and the response to stress or injury.

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Oncogenic Kras Induces Spatiotemporally Specific Tissue Deformation Through Converting Pulsatile Into Sustained ERK Activation

research Oncogenic Kras Induces Spatiotemporally Specific Tissue Deformation Through Converting Pulsatile Into Sustained ERK Activation

September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

The Kras mutation changes normal cell signals, leading to disrupted tissue structure and potential cancer.

research Undariopsis Peterseniana Promotes Hair Growth by the Activation of Wnt/β-Catenin and ERK Pathways

27 citations, May 2017 in “Marine Drugs”

Undariopsis peterseniana extract helps hair grow by activating certain cell growth pathways and could be a new treatment for hair loss.

Oncogenic Ras Mutation Induces Spatiotemporally Specific Tissue Deformation Through Converting Fluctuated Into Sustained ERK Activation

research Oncogenic Ras Mutation Induces Spatiotemporally Specific Tissue Deformation Through Converting Fluctuated Into Sustained ERK Activation

July 2022 in “Journal of Investigative Dermatology”

A specific mutation in Kras causes abnormal tissue changes by making a cell signal continuously active, which disrupts normal cell coordination.

research An ERK-Dependent Molecular Switch Antagonizes Fibrosis And Promotes Regeneration In Spiny Mice (Acomys)

June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

A specific molecular switch, driven by MAPK/ERK signaling, helps spiny mice heal wounds by regenerating skin instead of forming scars.

research TCDD-Induced Activation of Aryl Hydrocarbon Receptor Regulates the Skin Stem Cell Population

9 citations, January 2015 in “Medical hypotheses”

TCDD disrupts skin stem cells, causing skin issues like chloracne.

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community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 119 upvotes 8 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Wait, so retinol actually helps with hair growth? I heard it was the other way around a while ago and just accepted it..

in Treatment 6 upvotes 5 years ago

Retinol can help with hair growth, contrary to previous beliefs. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Red Ginseng Extract Promotes the Hair Growth in Cultured Human Hair Follicles

17 upvotes 6 years ago

The conversation is about hair loss treatments, specifically discussing the effectiveness of Red Ginseng Extract in promoting hair growth. Other treatments mentioned include Minoxidil, finasteride, and RU58841.