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GlossaryERK inhibitors

drugs that block proteins involved in cell signaling

ERK inhibitors are drugs or molecules that block the activity of ERK (Extracellular signal-Regulated Kinases), which are proteins involved in sending signals within cells. These signals can control various functions, including cell growth and division. By inhibiting ERK, these drugs can potentially treat conditions like cancer, where cell growth is uncontrolled, or even certain types of hair loss by affecting the pathways that regulate hair follicle activity.

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Adverse cutaneous reactions to the new second-generation tyrosine kinase inhibitors (dasatinib, nilotinib) in chronic myeloid leukemia

research Adverse cutaneous reactions to the new second-generation tyrosine kinase inhibitors (dasatinib, nilotinib) in chronic myeloid leukemia

25 citations , November 2013 in “Journal of the American Academy of Dermatology”

Many patients on new leukemia drugs had mild to moderate skin reactions.

research Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis

6 citations , December 2019 in “Frontiers in genetics”

GLI1 might protect against the start of skin cancer and is not linked to cancer severity.

research Therapeutic potential of endogenous stem cells and cellular factors for scar-free skin regeneration

9 citations , January 2019 in “Drug Discovery Today”

Using skin stem cells and certain molecules might lead to scar-free skin healing.

research The complex relationship between TFEB transcription factor phosphorylation and subcellular localization

344 citations , May 2018 in “EMBO journal”

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

Clinical management of cutaneous adverse events in patients on targeted anticancer therapies and immunotherapies: a national consensus statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology

research Clinical management of cutaneous adverse events in patients on targeted anticancer therapies and immunotherapies: a national consensus statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology

26 citations , October 2018 in “Clinical & Translational Oncology”

Spanish experts provided guidelines for treating skin side effects in cancer patients on new therapies, stressing early action and teamwork.

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community Wait, so retinol actually helps with hair growth? I heard it was the other way around a while ago and just accepted it..

in Treatment 6 upvotes 5 years ago

Retinol can help with hair growth, contrary to previous beliefs. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Red Ginseng Extract Promotes the Hair Growth in Cultured Human Hair Follicles

17 upvotes 6 years ago

The conversation is about hair loss treatments, specifically discussing the effectiveness of Red Ginseng Extract in promoting hair growth. Other treatments mentioned include Minoxidil, finasteride, and RU58841.